TRANSLABYRINTH ELECTRICAL-STIMULATION FOR THE INDUCTION OF IMMEDIATE-EARLY GENES IN THE GERBIL BRAIN-STEM

被引：26

作者：

KAUFMAN, GD ^{[1
]}

PERACHIO, AA ^{[1
]}

机构：

[1] UNIV TEXAS,MED BRANCH,DEPT OTOLARYNGOL,GALVESTON,TX 77555

来源：

BRAIN RESEARCH | 1994年 / 646卷 / 02期

关键词：

FOS; ZIF/268; VESTIBULAR; OTOLITH; SEMICIRCULAR CANAL; INFERIOR OLIVE; ANESTHETIC EFFECT;

D O I：

10.1016/0006-8993(94)90104-X

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Brainstem immediate-early gene (IEG) protein expression was induced following applications of current to the labyrinth in unanesthetized gerbils. Electrode placement, stimulus polarity, current intensity and waveform, and anesthetics all significantly affect IEG expression patterns. Direct currents of different polarity applied across the labyrinth produced IEG expression in vestibular nuclei and inferior olivary neurons in patterns similar to those seen after hemilabyrinthectomy or hypergravity stimulation.

引用

页码：345 / 350

页数：6

共 18 条

[1] TRANSCRIPTIONAL REGULATION BY FOS AND JUN INVITRO - INTERACTION AMONG MULTIPLE ACTIVATOR AND REGULATORY DOMAINS [J].

ABATE, C ;

LUK, D ;

CURRAN, T .

MOLECULAR AND CELLULAR BIOLOGY, 1991, 11 (07) :3624-3632

[2] EXPRESSION OF C-FOS-LIKE PROTEIN AS A MARKER FOR NEURONAL-ACTIVITY FOLLOWING NOXIOUS-STIMULATION IN THE RAT [J].

BULLITT, E .

JOURNAL OF COMPARATIVE NEUROLOGY, 1990, 296 (04) :517-530

[3] ACTIVITY-DEPENDENT EXPRESSION OF THE TRANSCRIPTION FACTOR ZIF268 REVEALS OCULAR DOMINANCE COLUMNS IN MONKEY VISUAL-CORTEX [J].

CHAUDHURI, A ;

CYNADER, MS .

BRAIN RESEARCH, 1993, 605 (02) :349-353

[4]

COURJON JH, 1987, EXP BRAIN RES, V66, P41

[5] THE USE OF C-FOS AS A METABOLIC MARKER IN NEURONAL PATHWAY TRACING [J].

DRAGUNOW, M ;

FAULL, R .

JOURNAL OF NEUROSCIENCE METHODS, 1989, 29 (03) :261-265

[6] RELATION BETWEEN DISCHARGE REGULARITY AND RESPONSES TO EXTERNALLY APPLIED GALVANIC CURRENTS IN VESTIBULAR NERVE AFFERENTS OF THE SQUIRREL-MONKEY [J].

GOLDBERG, JM ;

SMITH, CE ;

FERNANDEZ, C .

JOURNAL OF NEUROPHYSIOLOGY, 1984, 51 (06) :1236-1256

[7]

KAUFMAN GD, 1992, J NEUROSCI, V12, P4489

[8] BRAIN-STEM FOS EXPRESSION FOLLOWING ACUTE UNILATERAL LABYRINTHECTOMY IN THE RAT [J].

KAUFMAN, GD ;

ANDERSON, JH ;

BEITZ, AJ .

NEUROREPORT, 1992, 3 (10) :829-832

[9] ACTIVATION OF A SPECIFIC VESTIBULO-OLIVARY PATHWAY BY CENTRIPETAL ACCELERATION IN RAT [J].

KAUFMAN, GD ;

ANDERSON, JH ;

BEITZ, A .

BRAIN RESEARCH, 1991, 562 (02) :311-317

[10] OTOLITH-BRAIN STEM CONNECTIVITY - EVIDENCE FOR DIFFERENTIAL NEURAL ACTIVATION BY VESTIBULAR HAIR-CELLS BASED ON QUANTIFICATION OF FOS EXPRESSION IN UNILATERAL LABYRINTHECTOMIZED RATS [J].

KAUFMAN, GD ;

ANDERSON, JH ;

BEITZ, AJ .

JOURNAL OF NEUROPHYSIOLOGY, 1993, 70 (01) :117-127

← 1 2 →