SYNTHESIS OF 5',8-CYCLOPURINE AND OF 5',6-CYCLODIHYDROPYRIMIDINE NUCLEOSIDES USING INTRAMOLECULAR RADICAL CYCLIZATION BASED ON THE ARYL TELLURIDE RADICAL EXCHANGE PROCESS

被引：28

作者：

BARTON, DHR

GERO, SD

QUICLETSIRE, B

SAMADI, M

VINCENT, C

机构：

[1] INST CHIM SUBST NAT,CNRS,F-91198 GIF SUR YVETTE,FRANCE

[2] TEXAS A&M UNIV SYST,DEPT CHEM,COLLEGE STN,TX 77843

来源：

TETRAHEDRON | 1991年 / 47卷 / 45期

关键词：

D O I：

10.1016/S0040-4020(01)80885-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of C-cylopurine and C-cyclodihydropyrimidine nucleosides has been effected using 5'-aryltelluronucleosides. Generation of methyl radicals from the photolysis of the acetyl derivative of N-hydroxy-2-thiopyridone permitted, by radical exchange, the formation of 5'-nucleoside radicals which cyclized in satisfactory yields.

引用

收藏

页码：9383 / 9392

页数：10

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