THE TREATMENT OF DONOR SITES WITH CULTURED EPITHELIAL GRAFTS

被引：14

作者：

BLIGHT, A

FATAH, MF

DATUBOBROWN, DD

MOUNTFORD, EM

CHESHIRE, IM

机构：

[1] WORDSLEY HOSP,W MIDLANDS REG PLAST & JAW SURG UNIT,STOURBRIDGE,W MIDLANDS,ENGLAND

[2] BIRMINGHAM ACCID HOSP,SKIN CULTURE LAB,BIRMINGHAM B15 1NA,W MIDLANDS,ENGLAND

来源：

BRITISH JOURNAL OF PLASTIC SURGERY | 1991年 / 44卷 / 01期

关键词：

D O I：

10.1016/0007-1226(91)90169-K

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

In a significant number of elderly patients, the healing of split skin donor sites can be delayed. The cultured allogenic epithelial graft (CAG) has been reported to heal leg ulcers. The mechanism of action may be to improve the healing environment and thus stimulate the host skin cells. A clinical trial was undertaken to compare the healing rate of the donor sites of elderly patients using CAGs and two commercially available dressings. Compared to Jelonet(R), CAGs (p = 0.008) and OpSite(R) (p = 0.013) significantly reduced the number of patients with delayed healing. There was no significant difference between CAGs and the occlusive dressing, OpSite.

引用

收藏

页码：12 / 14

页数：3

相关论文

共 13 条

[1] REJECTION, AFTER A SLIGHTLY PROLONGED SURVIVAL-TIME, OF LANGERHANS CELL FREE ALLOGENEIC CULTURED EPIDERMIS USED FOR WOUND COVERAGE IN HUMANS [J].

AUBOCK, J ;

IRSCHICK, E ;

ROMANI, N ;

KOMPATSCHER, P ;

HOPFL, R ;

HEROLD, M ;

SCHULER, G ;

BAUER, M ;

HUBER, C ;

FRITSCH, P .

TRANSPLANTATION, 1988, 45 (04) :730-737

[2] SURVIVAL OF CULTURED ALLOGENEIC KERATINOCYTES TRANSPLANTED TO DEEP DERMAL BED ASSESSED WITH PROBE SPECIFIC FOR Y-CHROMOSOME [J].

BRAIN, A ;

PURKIS, P ;

COATES, P ;

HACKETT, M ;

NAVSARIA, H ;

LEIGH, I .

BRITISH MEDICAL JOURNAL, 1989, 298 (6678) :917-919

[3] ENHANCEMENT OF WOUND-HEALING BY TOPICAL TREATMENT WITH EPIDERMAL GROWTH-FACTOR [J].

BROWN, GL ;

NANNEY, LB ;

GRIFFEN, J ;

CRAMER, AB ;

YANCEY, JM ;

CURTSINGER, LJ ;

HOLTZIN, L ;

SCHULTZ, GS ;

JURKIEWICZ, MJ ;

LYNCH, JB .

NEW ENGLAND JOURNAL OF MEDICINE, 1989, 321 (02) :76-79

[4] SURVIVAL OF CULTURED ALLOGRAFTS IN PATIENTS WITH BURNS ASSESSED WITH PROBE SPECIFIC FOR Y-CHROMOSOME [J].

BURT, AM ;

PALLETT, CD ;

SLOANE, JP ;

OHARE, MJ ;

SCHAFLER, KF ;

YARDENI, P ;

ELDAD, A ;

CLARKE, JA ;

GUSTERSON, BA .

BRITISH MEDICAL JOURNAL, 1989, 298 (6678) :915-917

[5]

CLANCY JMP, 1988, J AM ACAD DERMATOL, V18, P1365

[6]

DAVIES JWL, 1984, BURNS, V10, P94

[7] THE MORBIDITY OF SPLIT-SKIN GRAFT DONOR SITES IN THE ELDERLY - THE CASE FOR MESH-GRAFTING THE DONOR SITE [J].

FATAH, MF ;

WARD, CM .

BRITISH JOURNAL OF PLASTIC SURGERY, 1984, 37 (02) :184-190

[8] USE OF OPSITE, A VAPOR PERMEABLE DRESSING, ON SKIN-GRAFT DONOR SITES [J].

JAMES, JH ;

WATSON, ACH .

BRITISH JOURNAL OF PLASTIC SURGERY, 1975, 28 (02) :107-110

[9] TREATMENT OF CHRONIC VENOUS ULCERS WITH SHEETS OF CULTURED ALLOGENIC KERATINOCYTES [J].

LEIGH, IM ;

PURKIS, PE ;

NAVSARIA, HA ;

PHILLIPS, TJ .

BRITISH JOURNAL OF DERMATOLOGY, 1987, 117 (05) :591-597

[10] GRAFTING OF CULTURED ALLOGENEIC EPIDERMIS ON 2ND-DEGREE AND 3RD-DEGREE BURN WOUNDS ON 26 PATIENTS [J].

MADDEN, MR ;

FINKELSTEIN, JL ;

STAIANOCOICO, L ;

GOODWIN, CW ;

SHIRES, GT ;

NOLAN, EE ;

HEFTON, JM .

JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1986, 26 (11) :955-962