PREPARATION OF OPTICALLY PURE L-2-HYDROXYALDEHYDES WITH YEAST TRANSKETOLASE

被引：56

作者：

EFFENBERGER, F

NULL, V

ZIEGLER, T

机构：

[1] Institut für Organische Chemie, Universität Stuttgart, W-7000 Stuttgart 80

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 36期

关键词：

D O I：

10.1016/S0040-4039(00)79121-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

L-2-Hydroxyaldehydes L-3 with a great variety of substituents in 3-position are obtained in good chemical and excellent optical yields by kinetic resolution in the transketolase-catalyzed reaction of racemic 2-hydroxyaldehydes with lithium hydroxypyruvate 4 where only the enantiomer (R)-3 reacts to 5-deoxy-D-xyluloses 5.

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页码：5157 / 5160

页数：4

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