POLYSIALIC ACID EXPRESSION IN THE SALAMANDER RETINA IS INDUCIBLE BY THYROXINE

被引：5

作者：

BECKER, CG ^{[1
]}

BECKER, T ^{[1
]}

SCHMIDT, A ^{[1
]}

ROTH, G ^{[1
]}

机构：

[1] UNIV BREMEN,INST BRAIN RES,D-28334 BREMEN,GERMANY

来源：

DEVELOPMENTAL BRAIN RESEARCH | 1994年 / 79卷 / 01期

关键词：

NEURAL CELL ADHESION MOLECULE; METAMORPHOSIS; PLEURODELES WALTL; THYROID HORMONE; RETINOIC ACID; PEDOMORPHOSIS;

D O I：

10.1016/0165-3806(94)90059-0

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Polysialylation of the neural cell adhesion molecule (NCAM) in the retina of Pleurodeles waltl is up-regulated during metamorphosis. Incubation of larvae in thyroxine permanently induced polysialic acid expression in the retina in a concentration-dependent but age-independent manner within 3 days of incubation (3 X 10(-7) M). Retinoic acid had no effect. This suggests direct hormonal regulation of a post-translational modification of NCAM in the amphibian retina.

引用

页码：140 / 146

页数：7

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