NUMBER, IDENTITY, AND SEQUENCE OF THE DROSOPHILA HEAD SEGMENTS AS REVEALED BY NEURAL ELEMENTS AND THEIR DELETION PATTERNS IN MUTANTS

被引:93
作者
SCHMIDTOTT, U [1 ]
GONZALEZGAITAN, M [1 ]
JACKLE, H [1 ]
TECHNAU, GM [1 ]
机构
[1] MAX PLANCK INST BIOPHYS CHEM,MOLEK ENTWICKLUNGBIOL ABT,D-37077 GOTTINGEN,GERMANY
关键词
D O I
10.1073/pnas.91.18.8363
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The development of the insect head tagma involves massive rearrangements and secondary fusions of segment anlagen during embryogenesis. Due to the lack of reliable morphological markers, the number, identity, and sequence of the head segments, particularly in the pregnathal region, are still a matter of ongoing debates. We examined the complex array of internal structures of the embryonic Drosophila melanogaster head such as the sensory structures and nerves of the peripheral and stomatogastric nervous systems, and we used embryonic head mutations causing a lack of overlapping segment anlagen to unravel the segmental identity and the sequence of the neural elements. Our results provide evidence for seven distinct segments in the Drosophila head, each characterized by a specific set of sensory neurons, consistent with the proposal that insects, myriapods, and crustaceans share a monophyletic evolutionary tree from a common annelid-like ancestor.
引用
收藏
页码:8363 / 8367
页数:5
相关论文
共 32 条
[1]  
ANDERSON DT, 1973, EMBRYOLOGY PHYLOGENY
[2]   SEARCHING FOR PATTERN AND MUTATION IN THE DROSOPHILA GENOME WITH A P-LACZ VECTOR [J].
BIER, E ;
VAESSIN, H ;
SHEPHERD, S ;
LEE, K ;
MCCALL, K ;
BARBEL, S ;
ACKERMAN, L ;
CARRETTO, R ;
UEMURA, T ;
GRELL, E ;
JAN, LY ;
JAN, YN .
GENES & DEVELOPMENT, 1989, 3 (09) :1273-1287
[3]   CONTROL AND FUNCTION OF TERMINAL GAP GENE ACTIVITY IN THE POSTERIOR POLE REGION OF THE DROSOPHILA EMBRYO [J].
BRONNER, G ;
JACKLE, H .
MECHANISMS OF DEVELOPMENT, 1991, 35 (03) :205-211
[4]  
Campos-Ortega J. A., 1985, EMBRYONIC DEV DROSOP
[5]  
CAPOVILLA M, 1992, DEVELOPMENT, V114, P99
[6]   THE TORSO RECEPTOR LOCALIZES AS WELL AS TRANSDUCES THE SPATIAL SIGNAL SPECIFYING TERMINAL BODY PATTERN IN DROSOPHILA [J].
CASANOVA, J ;
STRUHL, G .
NATURE, 1993, 362 (6416) :152-155
[7]  
COHEN S, 1991, TRENDS GENET, V7, P267
[8]   PROXIMAL DISTAL PATTERN-FORMATION IN DROSOPHILA - CELL AUTONOMOUS REQUIREMENT FOR DISTAL-LESS GENE ACTIVITY IN LIMB DEVELOPMENT [J].
COHEN, SM ;
JURGENS, G .
EMBO JOURNAL, 1989, 8 (07) :2045-2055
[9]   EXPRESSION AND EMBRYONIC FUNCTION OF EMPTY SPIRACLES - A DROSOPHILA HOMEO BOX GENE WITH 2 PATTERNING FUNCTIONS ON THE ANTERIOR POSTERIOR AXIS OF THE EMBRYO [J].
DALTON, D ;
CHADWICK, R ;
MCGINNIS, W .
GENES & DEVELOPMENT, 1989, 3 (12A) :1940-1956
[10]   THE ORTHODENTICLE GENE IS REGULATED BY BICOID AND TORSO AND SPECIFIES DROSOPHILA HEAD DEVELOPMENT [J].
FINKELSTEIN, R ;
PERRIMON, N .
NATURE, 1990, 346 (6283) :485-488