THE GENETIC-BASIS OF AUTOIMMUNE THYROID-DISEASE - TIME TO FOCUS ON CHROMOSOMAL LOCI OTHER THAN THE MAJOR HISTOCOMPATIBILITY COMPLEX (HLA IN MAN)

被引:25
作者
MCLACHLAN, SM [1 ]
机构
[1] UNIV CALIF SAN FRANCISCO, SAN FRANCISCO, CA 94121 USA
关键词
D O I
10.1210/jcem.77.3.8370683
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Extensive investigations have demonstrated associations between autoimmune thyroid diseases and HLA but the relative risks are low. Family studies provide a powerful method of investigating genetic factors involved in disease, However, recent data suggest that HLA-region genes are unlikely to determine inheritance of autoimmune thyroid disease (1). © 1993 by The Endocrine Society.
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收藏
页码:A605 / C605
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