EXCRETION OF ELECTROLYTES, FREE CORTISOL AND ALDOSTERONE-18-OXO-GLUCURONIDE IN 24-HR URINES OF THE MONGOLIAN GERBIL (MERIONES-UNGUICULATUS) - EFFECT OF LYSINE-VASOPRESSIN AND ADRENOCORTICOTROPIN ADMINISTRATION, AND OF CHANGES IN SODIUM-BALANCE

1. 1. Administration of lysine-vasopressin (LVP, 1 IU/animal) strongly reduced electrolyte excretion in 24 hr urines of adult male Mongolian gerbils, but had no effect on free Cortisol (C) or aldosterone-18-oxo-glucuronide (Aldo-gluc.) excretion. 2. 2. (1-24) ACTH, given at a dosage of 20 IU/animal, increased C and Aldo-gluc. excretion but did not influence electrolyte excretion. 3. 3. Fluid intake and potassium excretion were decreased in animals offered a control or a sodium-deficient diet; contrasting, excretion of C was stimulated. 4. 4. In contrast to other rodents, Aldo-gluc. excretion showed no changes in Mongolian gerbils offered a sodium-deficient diet, but was diminished in animals either fed a control diet or given saline (154 mmol/1) as drinking water. © 1990.