STEREOISOMERS OF TETRAHYDROTHIAMIN PYROPHOSPHATE, POTENT INHIBITORS OF THE PYRUVATE-DEHYDROGENASE MULTIENZYME COMPLEX FROM ESCHERICHIA-COLI

被引：42

作者：

LOWE, PN

LEEPER, FJ

PERHAM, RN

机构：

[1] UNIV CAMBRIDGE,DEPT BIOCHEM,CAMBRIDGE CB2 1QW,ENGLAND

[2] UNIV CAMBRIDGE,DEPT ORGAN & INORGAN CHEM,CHEM LAB,CAMBRIDGE CB2 1EW,ENGLAND

来源：

BIOCHEMISTRY | 1983年 / 22卷 / 01期

关键词：

D O I：

10.1021/bi00270a022

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：150 / 157

页数：8

共 31 条

[1] ON THE MECHANISM OF THIAMINE ACTION .4. EVIDENCE FROM STUDIES ON MODEL SYSTEMS [J].

BRESLOW, R .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1958, 80 (14) :3719-3726

[2] BINDING OF THIAMIN THIAZOLONE PYROPHOSPHATE TO MAMMALIAN PYRUVATE-DEHYDROGENASE AND ITS EFFECTS ON KINASE AND PHOSPHATASE-ACTIVITIES [J].

BUTLER, JR ;

PETTIT, FH ;

DAVIS, PF ;

REED, LJ .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1977, 74 (04) :1667-1674

[3] REDUCTION OF THIAZOLIUM SALTS WITH SODIUM BOROHYDRIDE .2. MECHANISM AND STEREOCHEMISTRY OF REDUCTION [J].

CLARKE, GM ;

SYKES, P .

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1967, (15) :1411-&

[4] USE OF DIMETHYL SUBERIMIDATE AND NOVEL PERIODATE-CLEAVABLE BIS(IMIDO ESTERS) TO STUDY QUATERNARY STRUCTURE OF PYRUVATE-DEHYDROGENASE MULTIENZYME COMPLEX OF ESCHERICHIA-COLI [J].

COGGINS, JR ;

HOOPER, EA ;

PERHAM, RN .

BIOCHEMISTRY, 1976, 15 (12) :2527-2533

[5] MECHANISMS OF THIAMINE-CATALYZED REACTIONS - A KINETIC ANALYSIS OF DECARBOXYLATION OF PYRUVATE BY 3,4-DIMETHYLTHIAZOLIUM ION IN WATER AND ETHANOL [J].

CROSBY, J ;

LIENHARD, GE .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1970, 92 (19) :5707-+

[6] MECHANISMS OF THIAMINE-CATALYZED REACTIONS - DECARBOXYLATION OF 2-(1-CARBOXY-1-HYDROXYETHYL)-3,4-DIMETHYLTHIAZOLIUM CHLORIDE [J].

CROSBY, J ;

STONE, R ;

LIENHARD, GE .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1970, 92 (09) :2891-&

[7] MOLECULAR-WEIGHT AND SYMMETRY OF THE PYRUVATE-DEHYDROGENASE MULTI-ENZYME COMPLEX OF ESCHERICHIA-COLI [J].

DANSON, MJ ;

HALE, G ;

JOHNSON, P ;

PERHAM, RN ;

SMITH, J ;

SPRAGG, P .

JOURNAL OF MOLECULAR BIOLOGY, 1979, 129 (04) :603-617

[8] INTRA-MOLECULAR COUPLING OF ACTIVE-SITES IN PYRUVATE-DEHYDROGENASE MULTI-ENZYME COMPLEX OF ESCHERICHIA-COLI [J].

DANSON, MJ ;

HOOPER, EA ;

PERHAM, RN .

BIOCHEMICAL JOURNAL, 1978, 175 (01) :193-198

[9]

DAWSON RMC, 1969, DATA BIOCH RES, P210

[10]

GUTOWSKI JA, 1976, J BIOL CHEM, V251, P2863

← 1 2 3 4 →