ROLE OF BRAIN MONOAMINES IN ANTICONVULSANT EFFECT OF IMIPRAMINE IN ALBINO-RATS

被引：4

作者：

BHATTACHARYA, SK ^{[1
]}

MUKHOPADHYAY, SN ^{[1
]}

REDDY, PKSP ^{[1
]}

DAS, PK ^{[1
]}

机构：

[1] BANARAS HINDU UNIV, INST MED SCI, DEPT PHARMACOL, VARANASI 221005, INDIA

来源：

PHARMACOLOGY | 1976年 / 14卷 / 05期

关键词：

D O I：

10.1159/000136625

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The role of brain monoamines in the anticonvulsant effect of imipramine was investigated in albino rats, against maximal electroshock-induced seizures, by using drugs [6-hydroxydopamine and reserpine] with well-defined effects on brain monoamines. A definite role is suggested for noradrenaline in imipramine anticonvulsant action. Dopamine and 5-hydroxytryptamine do not appear to be involved in this effect of imipramine.

引用

页码：428 / 434

页数：7

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