PRETREATMENT WITH MIFEPRISTONE (RU-486) REDUCES INTERVAL BETWEEN PROSTAGLANDIN ADMINISTRATION AND EXPULSION IN 2ND TRIMESTER ABORTION

被引：102

作者：

RODGER, MW ^{[1
]}

BAIRD, DT ^{[1
]}

机构：

[1] UNIV EDINBURGH,CTR REPROD BIOL,DEPT OBSTET & GYNAECOL,37 CHALMERS ST,EDINBURGH EH3 9EW,SCOTLAND

来源：

BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY | 1990年 / 97卷 / 01期

关键词：

D O I：

10.1111/j.1471-0528.1990.tb01714.x

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Summary. The effect of pretreatment with mifepristone on prostaglandin‐induced abortion was investigated in a double‐blind randomized trial involving 100 women in the second trimester of pregnancy. The women were randomly allocated to receive either 600 mg oral mifepristone or placebo tablets 36 h before the administration of gemeprost pessaries. The median interval between administration of prostaglandin and abortion was significantly shorter in the mifepristone group (6.8 h) compared with the placebo group (15.8 h). The women pretreated with mifepristone required significantly fewer gemeprost pessaries to induce abortion and experienced significantly less pain than the women who had received placebo. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：41 / 45

页数：5

共 14 条

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