MALIGNANT LEYDIG-CELL TUMOR OF THE TESTIS IN COMPLETE REMISSION ON O,P'-DICHLORODIPHENYL-DICHLOROETHANE

被引：17

作者：

VANDERHEM, KG ^{[1
]}

BOVEN, E ^{[1
]}

VANHENNIK, MB ^{[1
]}

PINEDO, HM ^{[1
]}

机构：

[1] FREE UNIV AMSTERDAM HOSP,DEPT CLIN ONCOL,DE BOELELAAN 1117,1081 HV AMSTERDAM,NETHERLANDS

来源：

JOURNAL OF UROLOGY | 1992年 / 148卷 / 04期

关键词：

TESTICULAR NEOPLASMS; LEYDIG CELL TUMOR; DDD; MITOTANE;

D O I：

10.1016/S0022-5347(17)36878-7

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

A 56-year-old patient is described who presented with retroperitoneal lymph node metastases 2 years after resection of a Leydig cell tumor of the left testis. The patient did not suffer from endocrinological imbalance. Surgical removal of the metastases alleviated abdominal symptoms for 1 year. o,p'-Dichlorodiphenyl-dichloroethane (o,p'-DDD) treatment was started at the time of recurrence of the retroperitoneal mass and the appearance of a hepatic metastasis. Tumors were remarkably responsive to o,p'-DDD, since 2 complete remissions could be obtained for extended periods. The o,p'-DDD was tolerated reasonably well and serum levels of 15 to 20 mg./l. were sustained for many months. Unfortunately, the patient could not be cured with this effective treatment.

引用

页码：1256 / 1259

页数：4

共 16 条

[1] MALIGNANT INTERSTITIAL-CELL TUMOR OF TESTIS TREATED WITH O,P-DDD [J].

ABELSON, D ;

BULASCHE.H ;

TROMMER, PR ;

VALDESDA.A .

METABOLISM, 1966, 15 (03) :242-&

[2]

AZER PC, 1981, CANCER, V47, P1251, DOI 10.1002/1097-0142(19810315)47:6<1251::AID-CNCR2820470604>3.0.CO

[3]

2-R

[4]

BOVEN E, 1984, CANCER-AM CANCER SOC, V53, P26, DOI 10.1002/1097-0142(19840101)53:1<26::AID-CNCR2820530107>3.0.CO

[5]

2-I

[6]

GABRILOVE JL, 1975, CANCER, V35, P1184, DOI 10.1002/1097-0142(197504)35:4<1184::AID-CNCR2820350425>3.0.CO

[7]

2-Z

[8]

GREM JL, 1986, CANCER, V58, P2116, DOI 10.1002/1097-0142(19861101)58:9<2116::AID-CNCR2820580925>3.0.CO

[9]

2-X

[10] MITOTANE (O,P'-DDD) [J].

GUTIERREZ, ML ;

CROOKE, ST .

CANCER TREATMENT REVIEWS, 1980, 7 (01) :49-55

← 1 2 →