ACETOGENIC ISOQUINOLINE ALKALOIDS .60. 5'-O-DEMETHYL-8-O-METHYL-7-EPI-DIONCOPHYLLINE-A AND ITS REGULARLY CONFIGURATED ATROPISOMER FROM TRIPHYOPHYLLUM-PELTATUM

被引：10

作者：

BRINGMANN, G ^{[1
]}

RUBENACKER, M ^{[1
]}

KOCH, W ^{[1
]}

KOPPLER, D ^{[1
]}

ORTMANN, T ^{[1
]}

SCHAFFER, M ^{[1
]}

ASSI, LA ^{[1
]}

机构：

[1] UNIV ABIDJAN,CTR NATL FLORIST CONSERVATOIRE & JARDIN BOT,ABIDJAN 22,COTE IVOIRE

来源：

PHYTOCHEMISTRY | 1994年 / 36卷 / 04期

关键词：

TRIPHYOPHYLLUM PELTATUM; DIONCOPHYLLACEAE; STEM BARK; 5'-O-DEMETHYL-8-O-METHYL-7-EPI-DIONCOPHYLLINE A; 5'-O-DEMETHYL-8-O-METHYL-DIONCOPHYLLINE A; NAPHTHYLISOQUINOLINE ALKALOIDS; BIARYLS; ATROPISOMERISM;

D O I：

10.1016/S0031-9422(00)90491-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The isolation and structure elucidation of two new minor naphthylisoquinoline alkaloids from the stem bark of Triphyophyllum peltatum is described. From extended spectroscopic investigations, mainly NMR and CD spectroscopy, one of the alkaloids is deduced to be 5'-O-demethyl-8-O-methyl-7-epi-dioncophylline A. This new natural product is, thus, the first dioncophylline A analogous naphthylisoquinoline alkaloid from T. peltatum with an opposite configuration at the biaryl axis. Moreover, low amounts of an additional new alkaloid were isolated, whose spectral data suggest 5'-O-demethyl-8-O-methyl-dioncophylline A, i.e. the corresponding 'normal' atropodiastereomer.

引用

页码：1057 / 1061

页数：5

共 12 条

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