EXTRACTION AND ANALYSIS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF ANTIBIOTICS IN A DRUG DELIVERY SYSTEM FOR FARMED FISH

被引：6

作者：

ROGSTAD, A ^{[1
]}

WENG, B ^{[1
]}

机构：

[1] APOTHEKERNES LAB AS,PHARMACEUT RES & DEV,N-0212 OSLO,NORWAY

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1993年 / 82卷 / 05期

关键词：

D O I：

10.1002/jps.2600820517

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Simple assays for extraction and determination of the concentrations of the antibiotics oxytetracycline, oxolinic acid, and flumequine in a drug dosage form for farmed fish are described. HPLC with UV detection was used in the analyses. The recovery of all three drugs was approximately 100%, and the precision varied from 0.5-3.0%. The methods are applicable to the production control, quality control, and stability control of the products.

引用

页码：518 / 520

页数：3

共 6 条

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[3]

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[4]

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[5] SOLID-PHASE EXTRACTION AND HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF FLUMEQUINE AND OXOLINIC ACID IN SALMON PLASMA [J].

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[6]

ROGSTAD A, 1989, J LIQ CHROMATOGR, V12, P3073

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