TRANSFORMATION OF FIBROBLASTS INTO ENDOTHELIAL-CELLS DURING ANGIOGENESIS

被引：9

作者：

KON, K

FUJIWARA, T

机构：

[1] EHIME UNIV,SCH MED,CTR LAB ANIM,SHIGENOBU,EHIME 79102,JAPAN

[2] EHIME COLL HLTH SCI,DEPT MED LAB TECHNOL,TOBE,EHIME 79121,JAPAN

来源：

CELL AND TISSUE RESEARCH | 1994年 / 278卷 / 03期

关键词：

NEOVASCULARIZATION; ENDOTHELIAL CELLS; FIBROBLASTS; CELL TRANSFORMATION; WOUND HEALING; AUTORADIOGRAPHY; RABBIT;

D O I：

暂无

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 [细胞生物学]; 090102 [作物遗传育种];

摘要：

Light- and electron-microscopic autoradiography have been used to study fibroblast transformation into endothelial cells in the formation of new blood vessels during wound healing in rabbit ear chambers. When cultured fibroblasts labeled with tritium thymidine were transplanted autologously into the chambers, newly formed blood vessels contained endothelial cells labeled with tritium thymidine. This result suggests that fibroblasts play a pivotal role in angiogenesis, as progenitors of endothelial cells in newly formed blood vessels.

引用

页码：625 / 628

页数：4

共 30 条

[1]

ALOISI M, 1970, VIRCHOWS ARCH B, V6, P350

[2]

ANGIOGENESIS IN WOUND-HEALING [J].