REACTION OF PEROXYNITRITE WITH OXYHEMOGLOBIN - INTERFERENCE WITH PHOTOMETRICAL DETERMINATION OF NITRIC-OXIDE

被引：66

作者：

SCHMIDT, K ^{[1
]}

KLATT, P ^{[1
]}

MAYER, B ^{[1
]}

机构：

[1] GRAZ UNIV,INST PHARMAKOL & TOXIKOL,A-8010 GRAZ,AUSTRIA

来源：

BIOCHEMICAL JOURNAL | 1994年 / 301卷

关键词：

D O I：

10.1042/bj3010645

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A frequently applied photometrical assay of NO is based on the reaction of NO with oxyhaemoglobin. This study shows that peroxynitrite induces spectral changes of oxyhaemoglobin identical with those elicited by NO. Like a variety of other agents, peroxynitrite did not interfere with NO measurements using a Clark-type electrode, demonstrating that electrochemical detection has an advantage over the oxyhaemoglobin method for specific determination of NO.

引用

页码：645 / 647

页数：3

共 17 条

[1]

[Anonymous], 2006, J PHYSIOL-LONDON, DOI DOI 10.1113/jphysiol.2006.116632

[2] APPARENT HYDROXYL RADICAL PRODUCTION BY PEROXYNITRITE - IMPLICATIONS FOR ENDOTHELIAL INJURY FROM NITRIC-OXIDE AND SUPEROXIDE [J].

BECKMAN, JS ;

BECKMAN, TW ;

CHEN, J ;

MARSHALL, PA ;

FREEMAN, BA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (04) :1620-1624

[3] KINETICS OF SUPEROXIDE DISMUTASE-CATALYZED AND IRON-CATALYZED NITRATION OF PHENOLICS BY PEROXYNITRITE [J].

BECKMAN, JS ;

ISCHIROPOULOS, H ;

ZHU, L ;

VANDERWOERD, M ;

SMITH, C ;

CHEN, J ;

HARRISON, J ;

MARTIN, JC ;

TSAI, M .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1992, 298 (02) :438-445

[4] KINETICS OF NITRIC-OXIDE AND HYDROGEN-PEROXIDE PRODUCTION AND FORMATION OF PEROXYNITRITE DURING THE RESPIRATORY BURST OF HUMAN NEUTROPHILS [J].

CARRERAS, MC ;

PARGAMENT, GA ;

CATZ, SD ;

PODEROSO, JJ ;

BOVERIS, A .

FEBS LETTERS, 1994, 341 (01) :65-68

[5] CORRELATION BETWEEN NITRIC-OXIDE FORMATION DURING DEGRADATION OF ORGANIC NITRATES AND ACTIVATION OF GUANYLATE-CYCLASE [J].

FEELISCH, M ;

NOACK, EA .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1987, 139 (01) :19-30

[6]

FLORIS R, 1993, EUR J BIOCHEM, V215, P767, DOI 10.1111/j.1432-1033.1993.tb18091.x

[7] AUTOXIDATION KINETICS OF AQUEOUS NITRIC-OXIDE [J].

FORD, PC ;

WINK, DA ;

STANBURY, DM .

FEBS LETTERS, 1993, 326 (1-3) :1-3

[8] CHEMISTRY OF PERNITRITES .I. KINETICS OF DECOMPOSITION OF PERNITROUS ACID [J].

HUGHES, MN ;

NICKLIN, HG .

JOURNAL OF THE CHEMICAL SOCIETY A -INORGANIC PHYSICAL THEORETICAL, 1968, (02) :450-&

[9] CONTROL OF CORONARY VASCULAR TONE BY NITRIC-OXIDE [J].

KELM, M ;

SCHRADER, J .

CIRCULATION RESEARCH, 1990, 66 (06) :1561-1575

[10] TOLERANCE AND CROSS-TOLERANCE BETWEEN SIN-1 AND NITRIC-OXIDE IN BOVINE CORONARY-ARTERIES [J].

KUKOVETZ, WR ;

HOLZMANN, S .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1989, 14 :S40-S46

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