EXHALED NITRIC-OXIDE CONCENTRATION AND AMNIOTIC-FLUID NITRITE CONCENTRATION DURING PREGNANCY

被引：31

作者：

MORRIS, NH

CARROLL, S

NICOLAIDES, KH

STEER, PJ

WARREN, JB

机构：

[1] UNIV LONDON KINGS COLL HOSP,HARRIS BIRTHRIGHT RES CTR FETAL MED,LONDON,ENGLAND

[2] NATL HEART & LUNG INST,DEPT APPL PHARMACOL,LONDON SW3 6LY,ENGLAND

来源：

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION | 1995年 / 25卷 / 02期

关键词：

AMNIOTIC FLUID; ENDOTHELIUM; LUNG; PREGNANCY NITRIC OXIDE;

D O I：

10.1111/j.1365-2362.1995.tb01539.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We have assessed fetal and maternal nitric oxide (NO) production in pregnancy. Exhaled NO and amniotic fluid nitrite concentrations were measured by chemiluminescence between 10 and 42 weeks of pregnancy. Exhaled NO concentrations did not alter significantly during gestation. In contrast, there was a significant change in mean amniotic fluid nitrite concentration in late pregnancy (P < 0.001). The finding of decreased amniotic nitrite concentrations after 37 weeks of gestation support the hypothesis that reduced NO production may contribute to increased uterine activity in late pregnancy.

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页码：138 / 141

页数：4

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