REGIONAL CEREBRAL BLOOD-FLOW MEASUREMENT USING TC-99M HMPAO SPECT IN A PATIENT WITH ADRENOLEUKODYSTROPHY

被引：7

作者：

MATSUDA, H

UESUGI, H

KAMATA, K

SUNOHARA, N

YAGISHITA, A

机构：

[1] NATL CTR HOSP MENTAL NERVOUS & MUSCULAR DISORDERS,NATL CTR NEUROL & PSYCHIAT,DEPT PSYCHIAT,TOKYO,JAPAN

[2] NATL CTR HOSP MENTAL NERVOUS & MUSCULAR DISORDERS,NATL CTR NEUROL & PSYCHIAT,DEPT NEUROL,TOKYO,JAPAN

[3] TOKYO METROPOLITAN NEUROL HOSP,DEPT NEURORADIOL,TOKYO,JAPAN

来源：

CLINICAL NUCLEAR MEDICINE | 1995年 / 20卷 / 01期

关键词：

D O I：

10.1097/00003072-199501000-00013

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Regional cerebral blood flow (rCBF) measurement using Tc-99m HMPAO angiography and SPECT was performed in a patient with adrenoleukodystrophy. The whole brain CBF showed great reduction to 31 ml/100 g/min as compared with an age-matched normal value of 45.9 ml/100 g/min. rCBF showed extremely decreased values of approximately 28 and 10 ml/100 g/min in bilateral frontal cortex and white matter respectively. The SPECT scan provided useful information on gray matter involvement to MRI findings of widespread white matter lesions. This quantitative nuclear medicine technique may contribute to pathophysiologic evaluation of adrenoleukodystrophy complementary with MRI.

引用

页码：52 / 54

页数：3

共 18 条

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