ASSISTED EJACULATION COMBINED WITH IN-VITRO FERTILIZATION - AN EFFECTIVE TECHNIQUE TREATING MALE-INFERTILITY DUE TO SPINAL-CORD INJURY

被引：11

作者：

HULTLING, C

LEVI, R

GAROFF, L

NYLUND, L

ROSENBORG, L

SJOBLOM, P

HILLENSJO, T

机构：

[1] Karolinska Institute, Stockholm

[2] Department of Obstetrics and Gynecology, Huddinge University Hospital, Stockholm

来源：

PARAPLEGIA | 1994年 / 32卷 / 07期

关键词：

SPINAL CORD INJURY; MALE INFERTILITY; IN-VITRO FERTILIZATION (IVF); PREGNANCY;

D O I：

10.1038/sc.1994.73

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Infertility due to spinal cord injury (SCI) in males has been identified for decades as an area of major concern and techniques for assisted ejaculation are available. There has not been an overall consensus regarding which type of assisted procreation is the most appropriate for these couples. We describe here our experience from a programme based on assisted ejaculation combined with in vitro fertilization (IVF). Twelve couples have been treated so far and altogether 22 cycles with ovum pick-up have been completed. Fertilisation of the oocytes was obtained in 18 of these cycles. The overall oocyte fertilisation rate was 49%. Embryo transfer took place in 17 cycles, leading to seven clinical pregnancies. Four of the pregnancies are delivered or are ongoing, whereas three ended in first trimester spontaneous abortion. Thus our initial experience suggests that assisted ejaculation in combination with IVF is an effective option for these couples.

引用

页码：463 / 467

页数：5

共 13 条

[1]

Levi R., Hulting C., Von Holst H., Ekholm J., A new tool for spinal cord injuries, Liikartidningen (Sweden), 89, pp. 3361-3364, (1992)

[2]

Linsenmeyer T.A., Perkash I., Infertility in men with spinal cord injury. Review article, Arch Phys Med Rehabil, 72, pp. 747-754, (1991)

[3]

Guttmann L., The effect of prostigmine on the reproductive functions in the spinal man, Proc 4Th [Nt Neurological Congr, 2, (1949)

[4]

Brindley G.S., The fertility in men with spinal injuries, Paraplegia, 22, (1984)

[5]

Seager S.W., Savastano J.A., Street J.W., Et al., Semen quality and penile erections in normal and chronic spinal non-human primates, J Urol, 131, (1984)

[6]

Denil J., Ohl D.A., Menge A.C., Et al., Functional characteristics of sperm obtained by electroejaculation, J Urol, 47, pp. 69-72, (1992)

[7]

Bennett C.J., Seager S.W., Washer E.A., McGuires E.J., Sexual dysfunction and electroejaculation in men with spinal cord injury: Review article, J Ural, 139, pp. 453-457, (1988)

[8]

Hultling C., Fredricsson B., Garoff L., Et al., Assisted ejaculation and IVF. A promising method to treat infertility in male SCIs, Liikartidningen (Sweden), 91, pp. 588-590, (1994)

[9]

Wikland, Nilsson M.L., Hansson R., Et al., Collection of human oocytes by the use of sonography, Fertil Steril, 39, pp. 603-608, (1983)

[10]

Lasalle B., Testart J., Renard J.P., Human embryo features that influence the success of cryopreserva- tion with the use of 1,2 propandediol, Fertil.Steril, 44, pp. 645-651, (1985)

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