THE USE OF LIPOSOMES IN PREDICTING THE BIOLOGICAL MOBILITY OF ARSENIC COMPOUNDS

被引：13

作者：

CULLEN, WR

NELSON, J

机构：

[1] Chemistry Department, University of British Columbia, Vancouver, British Columbia, V6T1Z1

来源：

APPLIED ORGANOMETALLIC CHEMISTRY | 1992年 / 6卷 / 02期

关键词：

ORGANOARSENIC; DIFFUSION; LIPOSOMES;

D O I：

10.1002/aoc.590060211

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Efflux studies of radio-labelled methylarsonic acid (MMA) and dimethylarsinic acid (DMA) encapsulated in liposomes afford the following permeability values for the two arsenicals: 1.4 x 10(-13) cm s-1 and 4.5 x 10(-11) cm s-1 for MMA and DMA, respectively. These data are compared with the octanol/water partition coefficients which are 7.4 x 10(-3) and 8.4 x 10(-3) for MMA and DMA, respectively.

引用

页码：179 / 183

页数：5

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