THE VOLTAGE-GATED CA2+ RELEASE CHANNEL IN THE VACUOLAR MEMBRANE OF SUGAR-BEET RESIDES IN 2 ACTIVITY STATES

被引：9

作者：

JOHANNES, E

SANDERS, D

机构：

[1] The Plant Laboratory, Biology Department, University of York, York, YO1 5YW

来源：

FEBS LETTERS | 1995年 / 365卷 / 01期

基金：

英国生物技术与生命科学研究理事会;

关键词：

CALCIUM CHANNEL; SIGNAL TRANSDUCTION; PATCH CLAMP; VACUOLE; BETA VULGARIS;

D O I：

10.1016/0014-5793(95)00424-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The voltage-gated Ca2+ release channel in the vacuolar membrane of sugar beet tap roots resides in two states which show similar reversal potentials in biionic conditions but differ dramatically in their single channel current and open frequency, State I has a unitary Ca2+ conductance of 3.9 +/- 0.5 pS and channel openings are rare at vacuolar resting potentials, After spontaneous and reversible transition into State II the unitary Ca2+ conductance increases three-fold, accompanied by a concomitant rise in channel activity over the physiological voltage range, The 15- to 19-fold increase in total Ca2+ current after the State I to State II transition could play an essential role in channel activation during signal transduction.

引用

页码：1 / 6

页数：6

共 24 条

[1] OPENING OF CA-2+ CHANNELS IN ISOLATED RED BEET ROOT VACUOLE MEMBRANE BY INOSITOL 1,4,5-TRISPHOSPHATE [J].