CLONING OF RAT LUTROPIN (LH) RECEPTOR ANALOGS LACKING THE SOYBEAN LECTIN DOMAIN

被引:50
作者
BERNARD, MP [1 ]
MYERS, RV [1 ]
MOYLE, WR [1 ]
机构
[1] RUTGERS STATE UNIV,ROBERT WOOD JOHNSON MED SCH,DEPT OBGYN,675 HOES LANE,PISCATAWAY,NJ 08854
关键词
Chorionic gonadotropin; Leucine repeat elements; Lutropin; Lutropin receptor; Soybean lectin;
D O I
10.1016/0303-7207(90)90034-6
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
cDNAs coding for rat ovarian luteinizing hormone receptor analogs lacking three of the leucine repeats were detected in a library which had been prepared from rat luteal tissue undergoing human chorionic gonadotropin-induced luteinization. These leucine repeats correspond to amino acids 206-267 and contain the portion of the receptor that is homologous to the soybean lectin. The cDNA library also contained a receptor analog lacking amino acids 321-700 which code for the transmembrane domain. S-l mapping suggests that this latter form constitutes approximately half of all receptor-related mRNA. © 1990.
引用
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页码:R19 / R23
页数:5
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