MYOCARDIAL-ISCHEMIA AFTER TREATMENT WITH METHOTREXATE, ETOPOSIDE AND CISPLATIN

被引：4

作者：

IGAWA, M ^{[1
]}

KADENA, H ^{[1
]}

OHKUCHI, T ^{[1
]}

UEDA, M ^{[1
]}

USUI, T ^{[1
]}

MATSUURA, H ^{[1
]}

机构：

[1] HIROSHIMA UNIV,SCH MED,DEPT UROL,KASUMI 1-2-3,MINAMI KU,HIROSHIMA 734,JAPAN

来源：

UROLOGIA INTERNATIONALIS | 1993年 / 50卷 / 02期

关键词：

MYOCARDIAL ISCHEMIA; METHOTREXATE; ETOPOSIDE; CDDP; INVASIVE BLADDER CANCER; VASCULAR COMPLICATION;

D O I：

10.1159/000282461

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Cisplatin exerts an additional influence on myocardial ischemia induced by the cardiovascular effects of etoposide. Two cases of myocardial ischemia related to combination chemotherapy with methotrexate, etoposide and cisplatin are reported. While the major toxicity associated with systemic chemotherapy is hematologic, it is suggested that, in elderly patients with increased incidence of atherosclerotic disease, special attention be given to vascular complications of antineoplastic agents.

引用

页码：98 / 100

页数：3

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