COMPARATIVE EFFECTS OF 2 CHEMOTHERAPEUTIC MOUTHRINSES ON THE DEVELOPMENT OF SUPRAGINGIVAL DENTAL PLAQUE AND GINGIVITIS

被引:130
作者
OVERHOLSER, CD [1 ]
MEILLER, TF [1 ]
DEPAOLA, LG [1 ]
MINAH, GE [1 ]
NIEHAUS, C [1 ]
机构
[1] UNIV MARYLAND, BALTIMORE COLL DENT SURG, SCH DENT, DEPT MICROBIOL, BALTIMORE, MD 21201 USA
关键词
clinical trial; gingivitis; Listerine; Peridex; plaque; stain;
D O I
10.1111/j.1600-051X.1990.tb01108.x
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Abstract A 6‐month double‐blind, controlled clinical study was completed with 124 healthy adult subjects to determine the efficacy of 2 mouthrinses, Listerine (LA) and Peridex (PX), used as supplements to regular oral hygiene measures in reducing supragingival dental plaque and gingivitis. Following screening examinations for entry levels of existing gingivitis and plaque, baseline gingival and plaque area indices, extrinsic tooth stain, supragingival calculus, bleeding and soft tissue condition were recorded. All subjects then received a complete dental porphylaxis to remove plaque, calculus and extrinsic stain. Subjects were randomly assigned to 1 of 3 groups and performed supervised rinses twice daily for 30 s in addition to their normal oral hygiene, for 6 months. All indices were again evaluated at 3 and 6 months. After 6 months, LA and PX significantly (p < 0.001) inhibited development of plaque by 36.1% and 50.3%, respectively, and the development of gingivitis by 35.9% and 30.5%, respectively, compared to a hydroalcohol control. PX was more effective in inhibiting plaque and both mouthrinses appeared to be equally effective in inhibiting gingivitis. LA patients did not develop significant levels of stain or supragingival calculus at 6 months, compared to baseline or control. PX patients developed significant levels of extrinsic stain and supragingival calculus compared to baseline and control. Though PX was more effective than LA in the control of plaque, this study indicates that both LA and PX were effective agents in a regimen for the control of plaque and gingivitis. Copyright © 1990, Wiley Blackwell. All rights reserved
引用
收藏
页码:575 / 579
页数:5
相关论文
共 18 条
[1]  
[Anonymous], 1986, J AM DENT ASSOC, V112, P529
[2]   EFFICACY OF MOUTHRINSES IN INHIBITING DENTAL PLAQUE AND GINGIVITIS IN MAN [J].
AXELSSON, P ;
LINDHE, J .
JOURNAL OF CLINICAL PERIODONTOLOGY, 1987, 14 (04) :205-212
[3]  
CATON JG, 1985, COMPEND CONTIN ED DE, V6, P89
[4]   THE USE OF CHLORHEXIDINE IN THE MANAGEMENT OF GINGIVITIS IN CHILDREN [J].
DELAROSA, M ;
STURZENBERGER, OP ;
MOORE, DJ .
JOURNAL OF PERIODONTOLOGY, 1988, 59 (06) :387-389
[5]  
DEPAOLA L, 1986, J DENTAL RES, V65
[6]   EFFICACY OF LISTERINE ANTISEPTIC IN INHIBITING THE DEVELOPMENT OF PLAQUE AND GINGIVITIS [J].
GORDON, JM ;
LAMSTER, IB ;
SEIGER, MC .
JOURNAL OF CLINICAL PERIODONTOLOGY, 1985, 12 (08) :697-704
[7]   6-MONTH STUDY OF THE EFFECTS OF A CHLORHEXIDINE MOUTHRINSE ON GINGIVITIS IN ADULTS [J].
GROSSMAN, E ;
REITER, G ;
STURZENBERGER, OP ;
DELAROSA, M ;
DICKINSON, TD ;
FERRETTI, GA ;
LUDLAM, GE ;
MECKEL, AH .
JOURNAL OF PERIODONTAL RESEARCH, 1986, 21 :33-43
[8]  
LAMSTER I B, 1983, Clinical Preventive Dentistry, V5, P12
[9]  
LANG NP, 1982, J PERIODONTAL RES, V17, P101, DOI 10.1111/j.1600-0765.1982.tb01135.x
[10]  
LOBENE R R, 1986, Clinical Preventive Dentistry, V8, P3