CHEMOPROPHYLAXIS OF MULTIDRUG-RESISTANT TUBERCULOUS INFECTION IN HIV-UNINFECTED INDIVIDUALS USING CIPROFLOXACIN AND PYRAZINAMIDE - A DECISION-ANALYSIS

被引：22

作者：

STEVENS, JP ^{[1
]}

DANIEL, TM ^{[1
]}

机构：

[1] CASE WESTERN RESERVE UNIV,SCH MED T505,CTR INT HLTH,CLEVELAND,OH 44106

来源：

CHEST | 1995年 / 108卷 / 03期

关键词：

CHEMOPROPHYLAXIS; CIPROFLOXACIN; DECISION ANALYSIS; PYRAZINAMIDE; TUBERCULOSIS;

D O I：

10.1378/chest.108.3.712

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Study objective: To evaluate the use of ciprofloxacin and pyrazinamide for the prophylaxis of individuals infected with multiply drug-resistant strains of Myco-bacterium tuberculosis, Design: Decision analysis, using software (SMLTREE). Probabilities based on published studies, with sensitivity analysis for each probability. Setting: Health-care workers infected with multidrug-resistant strains of M tuberculosis. Interventions: Prophylaxis with ciprofloxacin and pyrazinamide. Measurements and results: We calculated the utilities of taking or not taking prophylaxis with ciprofloxacin and pyrazinamide. The decision analysis favored the use of ciprofloxacin-pyrazinamide prophylaxis by a small margin. Conclusion: Ciprofloxacin-pyrazinamide prophylaxis should be considered for health-care workers infected with multiply drug-resistant M tuberculosis.

引用

页码：712 / 717

页数：6

共 21 条

[1]

ALLING DW, 1960, AM REV RESPIR DIS, V81, P839

[2] THE INFLUENCE OF EPIDEMIOLOGIC FACTORS ON DRUG-RESISTANCE RATES IN TUBERCULOSIS [J].

BARNES, PF .

AMERICAN REVIEW OF RESPIRATORY DISEASE, 1987, 136 (02) :325-328

[3] NATIONWIDE SURVEY OF DRUG-RESISTANT TUBERCULOSIS IN THE UNITED-STATES [J].

BLOCH, AB ;

CAUTHEN, GM ;

ONORATO, IM ;

DANSBURY, KG ;

KELLY, GD ;

DRIVER, CR ;

SNIDER, DE .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1994, 271 (09) :665-671

[4] DECISION-ANALYSIS, PUBLIC-HEALTH POLICY, AND ISONIAZID CHEMOPROPHYLAXIS FOR YOUNG-ADULT TUBERCULIN SKIN REACTORS [J].

COLICE, GL .

ARCHIVES OF INTERNAL MEDICINE, 1990, 150 (12) :2517-2522

[5]

COMSTOCK GW, 1979, AM REV RESPIR DIS, V119, P827

[6]

COMSTOCK GW, 1967, AM REV RESPIR DIS, V95, P935

[7]

Ferebee SH, 1969, ADV TUBERC RES, V17, P28

[8] THE EMERGENCE OF DRUG-RESISTANT TUBERCULOSIS IN NEW-YORK-CITY [J].

FRIEDEN, TR ;

STERLING, T ;

PABLOSMENDEZ, A ;

KILBURN, JO ;

CAUTHEN, GM ;

DOOLEY, SW .

NEW ENGLAND JOURNAL OF MEDICINE, 1993, 328 (08) :521-526

[9] TREATMENT OF 171 PATIENTS WITH PULMONARY TUBERCULOSIS RESISTANT TO ISONIAZID AND RIFAMPIN [J].

GOBLE, M ;

ISEMAN, MD ;

MADSEN, LA ;

WAITE, D ;

ACKERSON, L ;

HORSBURGH, CR .

NEW ENGLAND JOURNAL OF MEDICINE, 1993, 328 (08) :527-532

[10] ISONIAZID PREVENTIVE THERAPY FOR TUBERCULOSIS - DECISION-ANALYSIS CONSIDERING ETHNICITY AND GENDER [J].

JORDAN, TJ ;

LEWIT, EM ;

REICHMAN, LB .

AMERICAN REVIEW OF RESPIRATORY DISEASE, 1991, 144 (06) :1357-1360

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