PURIFICATION AND CHARACTERIZATION OF THE DOG HEPATIC CYTOCHROME-P-450 ISOZYME RESPONSIBLE FOR THE METABOLISM OF 2,2',4,4',5,5'-HEXACHLOROBIPHENYL

被引：112

作者：

DUIGNAN, DB ^{[1
]}

SIPES, IG ^{[1
]}

LEONARD, TB ^{[1
]}

HALPERT, JR ^{[1
]}

机构：

[1] SK&F LABS, PHILADELPHIA, PA 19101 USA

来源：

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 1987年 / 255卷 / 02期

关键词：

D O I：

10.1016/0003-9861(87)90396-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：290 / 303

页数：14

共 48 条

[31] MULTIPLE FORMS OF CYTOCHROME-P-450 AND THE IMPORTANCE OF MOLECULAR-BIOLOGY AND EVOLUTION [J].

NEBERT, DW ;

NEGISHI, M .

BIOCHEMICAL PHARMACOLOGY, 1982, 31 (14) :2311-2317

[32]

OMURA T, 1964, J BIOL CHEM, V239, P2370

[33] POLYCHLORINATED-BIPHENYLS (PCBS) AND POLYBROMINATED BIPHENYLS (PBBS) - BIOCHEMISTRY, TOXICOLOGY, AND MECHANISM OF ACTION [J].

SAFE, S .

CRC CRITICAL REVIEWS IN TOXICOLOGY, 1984, 13 (04) :319-395

[34] MANY ROLES OF CYTOCHROME-B5 IN HEPATIC MICROSOMES [J].

SCHENKMAN, JB ;

JANSSON, I ;

ROBIESUH, KM .

LIFE SCIENCES, 1976, 19 (05) :611-623

[35] METABOLISM OF 2,2',3,3',6,6'-HEXACHLOROBIPHENYL AND 2,2',4,4',5,5'-HEXACHLOROBIPHENYL BY HUMAN HEPATIC MICROSOMES [J].

SCHNELLMANN, RG ;

PUTNAM, CW ;

SIPES, IG .

BIOCHEMICAL PHARMACOLOGY, 1983, 32 (21) :3233-3239

[36]

SCHNELLMANN RG, 1984, THESIS U ARIZONA

[37]

SCHNELLMANN RG, 1985, REV BIOCHEM TOXICOL, V7, P247

[38] 2,4,5,2',4',5'-HEXACHLOROBIPHENY - DISTRIBUTION, METABOLISM, AND EXCRETION IN THE DOG AND THE MONKEY [J].

SIPES, IG ;

SLOCUMB, ML ;

PERRY, DF ;

CARTER, DE .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 1982, 65 (02) :264-272

[39]

Strobel H W, 1978, Methods Enzymol, V52, P89

[40]

SUWA Y, 1985, J BIOL CHEM, V260, P7980

← 1 2 3 4 5 →