REPRODUCIBILITY OF RESTING CEREBRAL BLOOD-FLOW MEASUREMENTS WITH H215O POSITRON EMISSION TOMOGRAPHY IN HUMANS

被引：67

作者：

MATTHEW, E

ANDREASON, P

CARSON, RE

HERSCOVITCH, P

PETTIGREW, K

COHEN, R

KING, C

JOHANSON, CE

PAUL, SM

机构：

[1] NIMH,NEUROSCI BRANCH,CLIN BRAIN IMAGING SECT,CEREBRAL BLOOD FLOW & METAB LAB,BETHESDA,MD 20892

[2] NIMH,DEPT NUCL MED,BETHESDA,MD 20892

[3] NIMH,DIV EPIDEMIOL & SERV RES,BETHESDA,MD 20892

[4] UNIFORMED SERV UNIV HLTH SCI,DEPT PSYCHIAT,BETHESDA,MD 20814

来源：

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM | 1993年 / 13卷 / 05期

关键词：

H215O POSITRON EMISSION TOMOGRAPHY; NORMALIZATION OF DATA; REGIONS OF INTEREST; REPRODUCIBILITY OF MEASUREMENT; RESTING CEREBRAL BLOOD FLOW;

D O I：

10.1038/jcbfm.1993.95

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Two consecutive measurements of resting CBF were carried out in normal volunteers (n = 25) using (H2O)-O-15 positron emission tomography. Absolute whole-brain blood flow (WBBF; ml 100 g-1 min-1, mean +/- SD) for the first (40.3 +/- 6.4) and second (39.3 +/- 6.5) measurements was not significantly different (mean % difference 2.3 +/- 8.7). Analysis of regions of interest showed no significant differences in absolute regional CBF (rCBF) and normalized (rCBF/WBBF) rCBF. Left-right differences were also not significant. These data demonstrate the reproducibility of resting CBF measurements in normal humans.

引用

页码：748 / 754

页数：7

共 16 条

[1] STRATEGY FOR THE MEASUREMENT OF REGIONAL CEREBRAL BLOOD-FLOW USING SHORT-LIVED TRACERS AND EMISSION TOMOGRAPHY
ALPERT, NM
ERIKSSON, L
CHANG, JY
BERGSTROM, M
LITTON, JE
CORREIA, JA
BOHM, C
ACKERMAN, RH
TAVERAS, JM
[J]. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1984, 4 (01) : 28 - 34
[2] XE-133 INHALATION METHOD - ANALYSIS OF REPRODUCIBILITY - SOME OF ITS PHYSIOLOGICAL IMPLICATIONS
BLAUENSTEIN, UW
HALSEY, JH
WILSON, EM
WILLS, EL
RISBERG, J
[J]. STROKE, 1977, 8 (01) : 92 - 102
[3] CAMERON O, 1987, J CEREB BLOOD FLO S1, V7, pS590
[4] DAUBE-WITHERSPOON M E, 1992, Journal of Nuclear Medicine, V33, P1010
[5] DAUBEWITHERSPOO.ME, 1987, J NUCL MED, V28, P211
[6] STIMULUS RATE DEPENDENCE OF REGIONAL CEREBRAL BLOOD-FLOW IN HUMAN STRIATE CORTEX, DEMONSTRATED BY POSITRON EMISSION TOMOGRAPHY
FOX, PT
RAICHLE, ME
[J]. JOURNAL OF NEUROPHYSIOLOGY, 1984, 51 (05) : 1109 - 1120
[7] QUANTITATIVE MEASUREMENT OF REGIONAL CEREBRAL BLOOD-FLOW AND OXYGEN-METABOLISM IN MAN USING O-15 AND POSITRON EMISSION TOMOGRAPHY - THEORY, PROCEDURE, AND NORMAL VALUES
FRACKOWIAK, RSJ
LENZI, GL
JONES, T
HEATHER, JD
[J]. JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1980, 4 (06) : 727 - 736
[8] EVALUATION OF REGIONAL DIFFERENCES OF TRACER APPEARANCE TIME IN CEREBRAL TISSUES USING [O-15]WATER AND DYNAMIC POSITRON EMISSION TOMOGRAPHY
IIDA, H
HIGANO, S
TOMURA, N
SHISHIDO, F
KANNO, I
MIURA, S
MURAKAMI, M
TAKAHASHI, K
SASAKI, H
UEMURA, K
[J]. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1988, 8 (02) : 285 - 288
[9] THE NITROUS OXIDE METHOD FOR THE QUANTITATIVE DETERMINATION OF CEREBRAL BLOOD FLOW IN MAN - THEORY, PROCEDURE AND NORMAL VALUES
KETY, SS
SCHMIDT, CF
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1948, 27 (04) : 476 - 483
[10] REGIONAL BLOOD-FLOW CHANGES IN LEFT CEREBRAL HEMISPHERE DURING WORD PAIR LEARNING AND RECALL
MAXIMILIAN, VA
PROHOVNIK, I
RISBERG, J
HAKANSSON, K
[J]. BRAIN AND LANGUAGE, 1978, 6 (01) : 22 - 31

← 1 2 →