THE LONGEST, REGULAR POLYPEPTIDE 3(10) HELIX AT ATOMIC RESOLUTION

被引：86

作者：

PAVONE, V ^{[1
]}

DIBLASIO, B ^{[1
]}

SANTINI, A ^{[1
]}

BENEDETTI, E ^{[1
]}

PEDONE, C ^{[1
]}

TONIOLO, C ^{[1
]}

CRISMA, M ^{[1
]}

机构：

[1] UNIV PADUA,DEPT ORGAN CHEM,CNR,BIOPOLYMER RES CTR,I-35131 PADUA,ITALY

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1990年 / 214卷 / 03期

关键词：

D O I：

10.1016/0022-2836(90)90279-U

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A synthetic, terminally blocked homodecapeptide from the Cα,α-dimethylated glycyl residue α-aminoisobutyric acid has been analyzed by single-crystal X-ray diffraction and the structure refined to R = 0.073. The compound crystallizes as a perfect 310 helix, stabilized by eight consecutive intramolecular NH ... OC hydrogen bonds. This is the first observation at atomic resolution of a regular polypeptide 310 helix as long as three complete turns. © 1990.

引用

页码：633 / 635

页数：3

共 11 条

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