THE HUMAN INTERLEUKIN-1 RECEPTOR ANTAGONIST (IL1RN) GENE IS LOCATED IN THE CHROMOSOME-2Q14 REGION

被引：64

作者：

PATTERSON, D

JONES, C

HART, I

BLESKAN, J

BERGER, R

GEYER, D

EISENBERG, SP

SMITH, MF

AREND, WP

机构：

[1] SYNERGEN INC,BOULDER,CO 80301

[2] UNIV COLORADO,HLTH SCI CTR,DEPT MED,DIV RHEUMATOL,DENVER,CO 80262

来源：

GENOMICS | 1993年 / 15卷 / 01期

关键词：

D O I：

10.1006/geno.1993.1025

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The gene for human interleukin-1 receptor antagonist (IL1RN) has been assigned to chromosome 2 on the basis of Southern blot analysis of a series of human-Chinese hamster cell hybrids. Using a yeast artificial chromosome containing the IL1RN gene as a probe, the human IL1RN gene was localized to the long arm of chromosome 2 at band 2q14.2 by fluorescence in situ hybridization. This site is near the positions of genes for human IL-1α, IL-1β, and types I and II IL-1 receptors, as reported by other laboratories. © 1993 Academic Press, Inc.

引用

页码：173 / 176

页数：4

共 23 条

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