CAUSE AND IMPACT OF PULMONARY-HYPERTENSION IN ISOLATED AORTIC-STENOSIS ON OPERATIVE MORTALITY FOR AORTIC-VALVE REPLACEMENT IN MEN

Significant pulmonary hypertension is considered to be an infrequent finding in patients with aortic stenosis (AS).1,2 When present, it is usually thought to be related to either markedly depressed left ventricular systolic function, or associated mitral valve or pulmonary disease.3,4 However, there are very few reports that examined the pathogenesis and clinical significance of pulmonary hypertension in isolated AS. Therefore, the objective of this study was to determine the incidence and pathophysiology of pulmonary hypertension in isolated AS, and its effect on operative mortality for aortic valve replacement. © 1992.