RAPID-DETERMINATION OF ANTIFUNGAL ACTIVITY BY FLOW-CYTOMETRY

被引：73

作者：

GREEN, L ^{[1
]}

PETERSEN, B ^{[1
]}

STEIMEL, L ^{[1
]}

HAEBER, P ^{[1
]}

CURRENT, W ^{[1
]}

机构：

[1] ELI LILLY & CO,LILLY RES LAB,INDIANAPOLIS,IN 46285

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1994年 / 32卷 / 04期

关键词：

D O I：

10.1128/JCM.32.4.1088-1091.1994

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We have developed a rapid assay of antifungal activity which utilizes How cytometry to detect accumulation of a vital dye in drug-damaged fungal cells. Results of these studies suggest that flow cytometry may provide an improved, rapid method for determining and comparing the antifungal activities of compounds with differing modes of action.

引用

页码：1088 / 1091

页数：4

共 25 条

[1] FLUCONAZOLE SUSCEPTIBILITY TESTING OF CANDIDA-ALBICANS - MICROTITER METHOD THAT IS INDEPENDENT OF INOCULUM SIZE, TEMPERATURE, AND TIME OF READING [J].