DETERMINATION OF BINDING CONSTANT OF METALLOENZYMES FOR THEIR ACTIVE-SITE METAL-ION FROM LIGAND INHIBITION DATA - THEORETICAL-ANALYSIS AND APPLICATION TO INHIBITION OF THERMOLYSIN BY 1,10-PHENANTHROLINE

被引：12

作者：

VOORDOUW, G ^{[1
]}

MILO, C ^{[1
]}

ROCHE, RS ^{[1
]}

机构：

[1] UNIV CALGARY,DEPT CHEM,BIOPOLYMER RES GRP,CALGARY T2N 1N4,ALBERTA,CANADA

来源：

ANALYTICAL BIOCHEMISTRY | 1976年 / 70卷 / 02期

关键词：

D O I：

10.1016/0003-2697(76)90452-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：313 / 326

页数：14

共 13 条

[1] MEASUREMENT OF ZINC DISSOCIATION CONSTANTS OF ALKALINE PHOSPHATASE FROM ESCHERICHIA COLI BY EQUILIBRATION WITH ZINC ION BUFFERS [J].

COHEN, SR ;

WILSON, IB .

BIOCHEMISTRY, 1966, 5 (03) :904-&

[2] METALLOCARBOXYPEPTIDASES - MECHANISM OF INHIBITION BY CHELATING AGENTS, MERCAPTANS, AND METAL IONS [J].

COOMBS, TL ;

FELBER, JP ;

VALLEE, BL .

BIOCHEMISTRY, 1962, 1 (05) :899-&

[3]

DIXON M, 1964, ENZYMES, P429

[4] INHIBITION OF NEUTRAL PROTEASES BY 1,10-PHENANTHROLINE [J].

FEDER, J ;

GARRETT, LR ;

KOCHAVI, D .

BIOCHIMICA ET BIOPHYSICA ACTA, 1971, 235 (02) :370-&

[5] A SPECTROPHOTOMETRIC ASSAY FOR NEUTRAL PROTEASE [J].

FEDER, J .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1968, 32 (02) :326-&

[6] INHIBITION OF THERMOLYSIN BY DIPEPTIDES [J].

FEDER, J ;

BROUGHAM, LR ;

WILDI, BS .

BIOCHEMISTRY, 1974, 13 (06) :1186-1189

[7] MECHANISM OF INHIBITION OF CARBOXYPEPTIDASE A BY 1,10-PHENANTHROLINE [J].

FELBER, JP ;

COOMBS, TL ;

VALLEE, BL .

BIOCHEMISTRY, 1962, 1 (02) :231-&

[8]

HOLMQUIST B, 1974, J BIOL CHEM, V249, P4601

[9]

HUNTER A, 1945, J BIOL CHEM, V157, P427

[10] THERMOLYSIN - A ZINC METALLOENZYME [J].

LATT, SA ;

HOLMQUIS.B ;

VALLEE, BL .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1969, 37 (02) :333-&

← 1 2 →