GLYCOSYLATED HEMOGLOBIN (HBA1C) IN IRON-DEFICIENCY AND VITAMIN-B12 DEFICIENCY

被引：74

作者：

GRAMHANSEN, P

ERIKSEN, J

MOURITSANDERSEN, T

OLESEN, L

机构：

[1] Department of Internal Medicine B, Section of Hematology, Aalborg Hospital, Aalborg

来源：

JOURNAL OF INTERNAL MEDICINE | 1990年 / 227卷 / 02期

关键词：

glycosylated haemoglobin (HbA[!sub]1c[!/sub]); iron deficiency anaemia; vitamin B12 deficiency anaemia;

D O I：

10.1111/j.1365-2796.1990.tb00131.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Abstract. Glycosylated haemoglobin (HbA1c) was measured in 10 patients with iron deficiency anaemia, 10 patients with vitamin B12 deficiency anaemia and 10 healthy controls. Initially there were no significant differences between the groups (P > 0.4), but after treatment with iron and vitamin B12 for 3 and 6 weeks, the glycosylated haemoglobin concentration decreased significantly (P < 0.01). It was concluded that glycosylated haemoglobin is a sensitive marker of the changes in the erythrocyte population that are observed when predominantly immature erythrocytes are being produced. 1990 Blackwell Publishing Ltd

引用

页码：133 / 136

页数：4

共 10 条

[1]

BROOKS AP, 1980, LANCET, V2, P141

[2] BIOSYNTHESIS OF HUMAN HEMOGLOBIN A1C - SLOW GLYCOSYLATION OF HEMOGLOBIN INVIVO [J].