APPLICATION OF THE GOLD(I)-CATALYZED ALDOL REACTION TO A STEREOSELECTIVE SYNTHESIS OF (2S,3R,4R,6E)-3-HYDROXY-4-METHYL-2-(METHYLAMINO)OCT-6-ENOIC ACID (= MEBMT1)), CYCLOSPORINS UNUSUAL AMINO-ACID

被引：46

作者：

TOGNI, A ^{[1
]}

PASTOR, SD ^{[1
]}

RIHS, G ^{[1
]}

机构：

[1] CIBA GEIGY AG,CENT FUNCT RES,CH-4002 BASEL,SWITZERLAND

来源：

HELVETICA CHIMICA ACTA | 1989年 / 72卷 / 07期

关键词：

D O I：

10.1002/hlca.19890720707

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：1471 / 1478

页数：8

共 41 条

[1] A SHORT SYNTHESIS OF ENANTIOMERICALLY PURE (2S,3R,4R,6E)-3-HYDROXY-4-METHYL-2-(METHYLAMINO)-6-OCTENOIC ACID, THE UNUSUAL C-9 AMINO-ACID FOUND IN THE IMMUNOSUPPRESSIVE PEPTIDE CYCLOSPORINE
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[3] BOSNICH B, 1986, NATO SERIES
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[6] HYDROLYSIS OF IMIDATE SALTS - STEREOELECTRONIC CONTROL IN CLEAVAGE OF HEMIORTHOAMIDE TETRAHEDRAL INTERMEDIATE
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[7] HYDROLYSIS OF CYCLIC UNSYMMETRICAL ANTI IMIDATE SALTS - NEW EVIDENCE FOR STEREOELECTRONIC CONTROL
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[8] ASYMMETRIC-SYNTHESIS OF ANTI-BETA-HYDROXY-ALPHA-AMINO ACIDS
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[J]. TETRAHEDRON LETTERS, 1987, 28 (01) : 39 - 42
[9] ASYMMETRIC GLYCINE ENOLATE ALDOL REACTIONS - SYNTHESIS OF CYCLOSPORINES UNUSUAL AMINO-ACID, MEBMT
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[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (21) : 6757 - 6761
[10] ASYMMETRIC-SYNTHESIS CATALYZED BY CHIRAL FERROCENYLPHOSPHINE METAL-COMPLEXES
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[J]. PURE AND APPLIED CHEMISTRY, 1988, 60 (01) : 7 - 12

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