QUERCETIN AND NARINGENIN - EFFECTS ON ULCER FORMATION AND GASTRIC-SECRETION IN RATS

被引：55

作者：

MARTIN, MJ

MOTILVA, V

DELALASTRA, CA

机构：

[1] Departemento de Farmacia y Tecnologí Farmaceutica, Laboratorio de Farmacodinamia, Facultad de Farmacia, Universidad de Sevilla, Seville

来源：

PHYTOTHERAPY RESEARCH | 1993年 / 7卷 / 02期

关键词：

FLAVONOIDS; ANTIULCER ACTIVITY; GASTRIC SECRETION; STRESS ULCER;

D O I：

10.1002/ptr.2650070211

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The antiulcerogenic effect of two flavonoids, quercetin and naringenin, in acute gastric ulcer (cold-restraint and pylorus-ligated) has been investigated. In both models quercetin and naringenin presented a significant decrease in ulcer index with respect to the control group. Nevertheless, in the Shay-ligated method no decrease in either volume, acidity or pepsin were observed, however, a significant difference was found in histamine secretion values.

引用

页码：150 / 153

页数：4

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