ALLERGOLOGICAL EVALUATION FOR WORKERS EXPOSED TO TOLUENE DIISOCYANATE

被引:8
作者
HUANG, J [1 ]
WANG, XP [1 ]
UEDA, A [1 ]
AOYAMA, K [1 ]
CHEN, BM [1 ]
MATSUSHITA, T [1 ]
机构
[1] HUNAN MED UNIV,ENVIRONM MED LAB,CHANGSHA,PEOPLES R CHINA
关键词
TOLUENE DIISOCYANATE; ALLERGY; ASTHMA; CONTACT DERMATITIS;
D O I
10.2486/indhealth.29.85
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
A cross-sectional investigation for allergology was performed of 15 painters exposed to high concentrations of toluene diisocyanate (TDI) (0.07-0.17 ppm) during the process of handling polyurethane varnish in a furniture manufacturing factory. Asthmatic reactions such as dyspnea, wheezing related to workshifts and contact dermatitis were observed in four and three cases respectively by questionnaire survey. Lung function tests on the painters showed significant decline in FEV1, %FEV1 and MMF compared to the referents. An increment in mast cell degranulation percentage could be seen in the painters. And also, patch testing with TDI were positive in five cases. From the results, it was suggested that both allergic pulmonary effects and contact sensitization had occured in TDI-exposed painters in this factory.
引用
收藏
页码:85 / 92
页数:8
相关论文
共 23 条
[1]   DETECTION OF IMMUNOLOGICALLY SENSITIZED ISOCYANATE WORKERS BY RAST AND INTRACUTANEOUS SKIN-TESTS [J].
BAUR, X ;
DEWAIR, M ;
FRUHMANN, G .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1984, 73 (05) :610-618
[2]   ISOCYANATE-INDUCED PULMONARY-DISEASES - A CURRENT PERSPECTIVE [J].
BERNSTEIN, IL .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1982, 70 (01) :24-31
[3]   RADIOALLERGOSORBENT TESTING OF TOLUENE DIISOCYANATE-REACTIVE INDIVIDUALS USING PARA-TOLYL ISOCYANATE ANTIGEN [J].
BUTCHER, BT ;
ONEIL, CE ;
REED, MA ;
SALVAGGIO, JE .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1980, 66 (03) :213-216
[4]   TOLUENE DIISOCYANATE (TDI) PULMONARY-DISEASE - IMMUNOLOGICAL AND INHALATION CHALLENGE STUDIES [J].
BUTCHER, BT ;
SALVAGGIO, JE ;
WEILL, H ;
ZISKIND, MM .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1976, 58 (01) :89-100
[5]   SPECIFIC SERUM ANTIBODIES AGAINST ISOCYANATES - ASSOCIATION WITH OCCUPATIONAL ASTHMA [J].
CARTIER, A ;
GRAMMER, L ;
MALO, JL ;
LAGIER, F ;
GHEZZO, H ;
HARRIS, K ;
PATTERSON, R .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1989, 84 (04) :507-514
[6]  
Fregert S., 1981, MANUAL CONTACT DERMA, P71
[7]  
FUCHS S, 1951, Arch Mal Prof, V12, P191
[8]  
GIRSH LS, 1982, ALLERGOL IMMUNOPATH, V10, P229
[10]  
KAROL MH, 1989, J OCCUP MED, V23, P741