OUTCOME OF INADVERTENT ADMINISTRATION OF A GONADOTROPIN-RELEASING-HORMONE AGONIST (BUSERELIN) IN EARLY-PREGNANCY

被引：26

作者：

CAHILL, DJ ^{[1
]}

FOUNTAIN, SA ^{[1
]}

FOX, R ^{[1
]}

FLEMING, CF ^{[1
]}

BRINSDEN, PR ^{[1
]}

HULL, MGR ^{[1
]}

机构：

[1] BOURN HALL CLIN,CAMBRIDGE CB3 7TR,ENGLAND

来源：

HUMAN REPRODUCTION | 1994年 / 9卷 / 07期

关键词：

EARLY PREGNANCY; INADVERTENT GNRH ANALOG; PREGNANCY OUTCOME;

D O I：

10.1093/oxfordjournals.humrep.a138686

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

All women undergoing pituitary down-regulation before planned in-vitro fertilization (IVF) treatment in two IVF units were studied to assess the risks of and to pregnancies occurring inadvertently when gonadotrophin-releasing hormone agonists (GnRHa) were used to achieve pituitary desensitization during the luteal phase prior to planned NF treatment. In 2670 cycles, 25 women conceived (0.9% of cycles). Of these, three resulted in pre-clinical abortions (12%) but there were no clinical abortions, and 22 have ended with live births at term of apparently normal infants. Collation of these and other published data suggest that pregnancy outcome is not adversely affected by GnRHa administration in the luteal phase of the conception cycle.

引用

页码：1243 / 1246

页数：4

共 32 条

[1] INADVERTENT GONADOTROPIN-RELEASING-HORMONE AGONIST (GNRHA) ADMINISTRATION IN THE LUTEAL-PHASE MAY IMPROVE FECUNDITY IN IN-VITRO FERTILIZATION PATIENTS [J].