PETSIM - MONTE-CARLO SIMULATION OF ALL SENSITIVITY AND RESOLUTION PARAMETERS OF CYLINDRICAL POSITRON IMAGING-SYSTEMS

被引:74
作者
THOMPSON, CJ [1 ]
MORENOCANTU, J [1 ]
PICARD, Y [1 ]
机构
[1] MCGILL UNIV,MED PHYS UNIT,MONTREAL H3A 2B4,QUEBEC,CANADA
关键词
D O I
10.1088/0031-9155/37/3/017
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Monte Carlo simulation techniques are applied to track the annihilation photons from positron decay, and store the photon histories. Reasonably realistic models of the isotope distribution in the brain and heart during typical PET studies, as well as the traditional phantoms used for measuring PET scanner performance can be built out of up to 10 hollow or solid cylinders. Separate programs model the source distribution and its attenuation characteristics, the collimators and the detectors. These modules are connected by compact gamma history files which are stored on disc or tape. Over 50 million gamma ray histories can be saved on a 1 Gbyte disc, representing the decay of several billion atoms. This allows for good precision even for single thin slices in scanners with wide axial acceptance. The simulation results include spectrum analysis, sensitivity to true coincident events, scattered coincident and single rays, and the effects on these parameters of detector dead time. The storage of intermediate results on tape reduces simulation time, since most common source geometries need be generated only once. The sensitivities in multi-slice systems are presented as matrices of coincident crystal planes. The matrix shows the true count sensitivity and the scatter fraction together for each valid combination of planes. This presentation is very useful for assessing the effects of various degrees of inter-plane collimation. The spatial resolution analysis includes the effects of positron range, non-collinearity of the gamma rays, multiple interaction within the detectors, and the effects of quantization into single crystals in multiple-crystal block detectors. Each of these effects can be turned on or off without repeating the simulation. Both in-plane and axial resolutions are calculated as a function of location of the positron-emitting nucleus and the angle of incidence of gamma rays on the crystals. Single crystals, blocks and crystals with depth of interaction encoding can be specified, as can the method of backprojection (planar, or 3D), so that the detector geometry can be optimized.
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收藏
页码:731 / 749
页数:19
相关论文
共 28 条
[1]  
BERGER MJ, 1990, STANDARD REFERENCE D
[2]   A MULTICRYSTAL 2-DIMENSIONAL BGO DETECTOR SYSTEM FOR POSITRON EMISSION TOMOGRAPHY [J].
CASEY, ME ;
NUTT, R .
IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1986, 33 (01) :460-463
[3]   A NEW APPROACH TO VERY HIGH-RESOLUTION MINI-BRAIN PET USING A SMALL NUMBER OF LARGE DETECTORS [J].
CHO, ZH ;
JUH, SC ;
FRIEDENBERG, RM ;
BUNNEY, W ;
BUCHSBAUM, M ;
WONG, E .
IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1990, 37 (02) :842-851
[4]   HIGH-RESOLUTION BRAIN PET WITH LARGE DETECTORS .2. PERFORMANCE STUDY [J].
CHO, ZH ;
JUH, SC .
IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1991, 38 (02) :726-731
[5]   PERFORMANCE FIGURES AND IMAGES FROM THE THERASCAN-3128 POSITRON EMISSION TOMOGRAPH [J].
COOKE, BE ;
EVANS, AC ;
FANTHOME, EO ;
ALARIE, R ;
SENDYK, AM .
IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1984, 31 (01) :640-644
[6]   A STUDY OF THE POSSIBILITY OF USING MULTI-SLICE PET SYSTEMS FOR 3D IMAGING [J].
DAHLBOM, M ;
ERIKSSON, L ;
ROSENQVIST, G ;
BOHM, C .
IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1989, 36 (01) :1066-1071
[7]  
DAHLBOM M, 1987, IEEE T MED IMAGING, V7, P264
[8]   INITIAL RESULTS FROM THE DONNER-600 CRYSTAL POSITRON TOMOGRAPH [J].
DERENZO, SE ;
HUESMAN, RH ;
CAHOON, JL ;
GEYER, A ;
UBER, D ;
VULETICH, T ;
BUDINGER, TF .
IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1987, 34 (01) :321-325
[9]  
DERENZO SE, 1979, POSITRON ANNIHILATIO, P819
[10]   PERFORMANCE EVALUATION OF THE PC-2048 - A NEW 15-SLICE ENCODED-CRYSTAL PET SCANNER FOR NEUROLOGICAL STUDIES [J].
EVANS, AC ;
THOMPSON, CJ ;
MARRETT, S ;
MEYER, E ;
MAZZA, M .
IEEE TRANSACTIONS ON MEDICAL IMAGING, 1991, 10 (01) :90-98