CHEMICAL CONVERSION OF A DNA-BINDING PROTEIN INTO A SITE-SPECIFIC NUCLEASE

被引：129

作者：

CHEN, CHB ^{[1
]}

SIGMAN, DS ^{[1
]}

机构：

[1] UNIV CALIF LOS ANGELES,SCH MED,DEPT BIOL CHEM,LOS ANGELES,CA 90024

来源：

SCIENCE | 1987年 / 237卷 / 4819期

关键词：

D O I：

10.1126/science.2820056

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：1197 / 1201

页数：5

共 12 条

[1] ARVIDSON DN, 1986, J BIOL CHEM, V261, P238
[2] NUCLEASE ACTIVITY OF 1,10-PHENANTHROLINE COPPER - SEQUENCE-SPECIFIC TARGETING
CHEN, CHB
SIGMAN, DS
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[3] NONENZYMATIC SEQUENCE-SPECIFIC CLEAVAGE OF SINGLE-STRANDED-DNA
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ORGEL, LE
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (04) : 963 - 967
[4] SEQUENCE-SPECIFIC CLEAVAGE OF SINGLE-STRANDED-DNA - OLIGODEOXYNUCLEOTIDE-EDTA.FE(II)
DREYER, GB
DERVAN, PB
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (04) : 968 - 972
[5] NUCLEOTIDE-SEQUENCE AND EXPRESSION OF ESCHERICHIA-COLI TRPR, THE STRUCTURAL GENE FOR THE TRP APOREPRESSOR
GUNSALUS, RP
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (12): : 7117 - 7121
[6] CLEAVAGE OF DOUBLE HELICAL DNA BY (METHIDIUMPROPYL-EDTA)IRON(II)
HERTZBERG, RP
DERVAN, PB
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1982, 104 (01) : 313 - 315
[7] ADDITION OF SULFHYDRYL-GROUPS TO ESCHERICHIA-COLI RIBOSOMES BY PROTEIN MODIFICATION WITH 2-IMINOTHIOLANE (METHYL 4-MERCAPTOBUTYRIMIDATE)
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[J]. BIOCHEMISTRY, 1978, 17 (25) : 5399 - 5406
[8] MUTATIONAL STUDIES WITH THE TRP REPRESSOR OF ESCHERICHIA-COLI SUPPORT THE HELIX-TURN-HELIX MODEL OF REPRESSOR RECOGNITION OF OPERATOR DNA
KELLEY, RL
YANOFSKY, C
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (02) : 483 - 487
[9] ESCHERICHIA-COLI TRYPTOPHAN REPRESSOR BINDS MULTIPLE SITES WITHIN THE AROH AND TRP OPERATORS
KUMAMOTO, AA
MILLER, WG
GUNSALUS, RP
[J]. GENES & DEVELOPMENT, 1987, 1 (06) : 556 - 564
[10] THE 3-DIMENSIONAL STRUCTURE OF TRP REPRESSOR
SCHEVITZ, RW
OTWINOWSKI, Z
JOACHIMIAK, A
LAWSON, CL
SIGLER, PB
[J]. NATURE, 1985, 317 (6040) : 782 - 786

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