CARBON-NITROGEN BOND FORMATION IN CYCLIZATION BY DEOXYGENATION, THERMOLYSIS OR PHOTOLYSIS OF PHENYLIMIDAZO[1,2-A][1,8]NAPHTHYRIDINES

被引：12

作者：

GUEIFFIER, A

BLACHE, Y

VIOLS, H

CHAPAT, JP

CHAVIGNON, O

TEULADE, JC

DAUPHIN, G

DEBOUZY, JC

CHABARD, JL

机构：

[1] UFR PHARM,CHIM ORGAN PHARMACEUT LAB,RECH PHARMACOCHIM GRP,F-63001 CLERMONT FERRAND,FRANCE

[2] LAB CHIM ORGAN BIOL,CNRS,URA 485,F-63170 CLERMONT FERRAND,FRANCE

[3] CTR RECH SERV SANTE ARMEES,BIOPHYS LAB,F-38702 LA TRONCHE,FRANCE

[4] UFR PHARM,CHIM ANALYT & SPECTROMETRIE MASSE,RECH BIODYNAM MEDICAMENT GRP,F-63001 CLERMONT FERRAND,FRANCE

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1992年 / 29卷 / 02期

关键词：

D O I：

10.1002/jhet.5570290202

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Triethyl phosphite deoxygenation of 2-(2-nitrophenyl)imidazo[1,2-a][1,8]naphthyridine (3) led to the C-insertion to give the indoloimidazonaphthyridine 5. Our attempt to promote the N-insertion by blocking the C-3 position failed. Triethyl phosphite deoxygenation of 1-nitroso-2-(4-fluorophenyl)imidazo[1,2-a][1,8]-naphthyridine (12) led to the corresponding amine structure (15). Thermolysis and photolysis of 6,8-dimethyl-2-(2-azidophenyl)imidazo[1,2-a][1,8]naphthyridine (17) are also reported.

引用

收藏

页码：283 / 287

页数：5

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