MUTAGENICITY OF THE COMPONENTS OF OZONATED HUMIC SUBSTANCE

被引：12

作者：

MATSUDA, H

OSE, Y

NAGASE, H

SATO, T

KITO, H

SUMIDA, K

机构：

[1] GIFU CITY WOMENS COLL,GIFU 502,JAPAN

[2] GIFU COLL PHARM,DEPT PUBL HLTH,GIFU 502,JAPAN

来源：

SCIENCE OF THE TOTAL ENVIRONMENT | 1991年 / 103卷 / 2-3期

关键词：

D O I：

10.1016/0048-9697(91)90139-6

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Eight components of humic substances were ozonated. Mutagenic activity was found with TA100 with and without S9 mix for all ozonated components. Ozonated products of p-hydroxybenzaldehyde were separated into five fractions by silica gel chromatography and each fraction subjected to mutagenicity assay. Mutagenic activity was found in the chloroform and chloroform-acetone (1:1) fractions. The compounds in these fractions were identified, and aldehydes such as formaldehyde, acetaldehyde, glyoxal, glyoxylic acid and methyl glyoxal were found to be mutagenic. Mutagenic compounds are present in the polar fraction.

引用

页码：129 / 140

页数：12

共 43 条

[1] MUTAGENICITY OF 1,2-DICARBONYL COMPOUNDS - MALTOL, KOJIC ACID, DIACETYL AND RELATED SUBSTANCES [J].