STUDIES TOWARD STRUCTURE-ACTIVITY-RELATIONSHIPS OF TAXOL(R) - SYNTHESIS AND CYTOTOXICITY OF TAXOL(R) ANALOGS WITH C-2' MODIFIED PHENYLISOSERINE SIDE-CHAINS

被引：50

作者：

KANT, J

HUANG, S

WONG, H

FAIRCHILD, C

VYAS, D

FARINA, V

机构：

[1] Bristol-Myers Squibb, Pharmaceutical Research Institute, Wallingford, CT 06492-7660

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 11期

关键词：

D O I：

10.1016/S0960-894X(01)80980-X

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Analogues of taxol with a modified phenylisoserine side chains were synthesized and evaluated as potential cytotoxic agents.

引用

页码：2471 / 2474

页数：4

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