SLOW-RELEASE 5-AMINO-SALICYLIC ACID (PENTASA) FOR THE TREATMENT OF ACTIVE CROHNS-DISEASE

被引：65

作者：

MAHIDA, YR ^{[1
]}

JEWELL, DP ^{[1
]}

机构：

[1] RADCLIFFE INFIRM, GASTROENTEROL UNIT, WOODSTOCK RD, OXFORD OX2 6HE, ENGLAND

来源：

DIGESTION | 1990年 / 45卷 / 02期

关键词：

5-amino-salicylic acid; Crohn's disease; mesalazine; Pentasa®;

D O I：

10.1159/000200228

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

A double-blind, placebo-controlled trial of a slow-release preparation of 5-amino-salicylic acid (Pentasa®) has been performed in 40 patients with active Crohn's disease. Over a 6-week period, Pentasa (1.5 g daily) was no different to the dummy tablet in terms of clinical activity (Harvey-Bradshaw Index) or laboratory indicators of inflammation. No serious adverse reactions occurred.

引用

页码：88 / 92

页数：5

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