METALLOPROTEINASES IN THE LARVAE OF ECHINOCOCCUS-GRANULOSUS

被引：29

作者：

MARCO, M

NIETO, A

机构：

[1] Cátedra de Inmunologia, Facultad de Quimica, Montevideo

来源：

INTERNATIONAL JOURNAL FOR PARASITOLOGY | 1991年 / 21卷 / 06期

关键词：

ECHINOCOCCUS-GRANULOSUS; HYDATID DISEASE; HYDATIDOSIS; METACESTODE; METALLOPROTEINASES; PROTEINASES;

D O I：

10.1016/0020-7519(91)90091-K

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Proteolytic activity in hydatid cyst fluid, cyst membranes and protoscoleces of E. granulosus was analyzed by electrophoresis in gelatin-containing polyacrylamide gels, including characterization with a set of protease inhibitors. All contained metalloproteinases in the range 60-120 kDa, with neutral/alkaline pH optima. Major activity was observed in hydatid fluid and the membranes (five bands) with both exhibiting similar electrophoretic patterns. The samples prepared from protoscoleces shared only some of these bands.

引用

页码：743 / 746

页数：4

共 9 条

[1] PROTEOLYTIC CLEAVAGE OF IGG BOUND TO THE FC RECEPTOR OF SCHISTOSOMA-MANSONI SCHISTOSOMULA [J].