DIRECT OBSERVATION OF A TETRAHEDRAL BORONIC ACID BETA-LACTAMASE COMPLEX USING B-11 NMR-SPECTROSCOPY

被引:21
作者
BALDWIN, JE
CLARIDGE, TDW
DEROME, AE
SMITH, BD
TWYMAN, M
WALEY, SG
机构
[1] OXFORD CTR MOLEC SCI, INORGAN CHEM LAB, OXFORD OX1 3QY, ENGLAND
[2] OXFORD CTR MOLEC SCI, MOLEC BIOPHYS LAB, OXFORD OX1 3QY, ENGLAND
关键词
D O I
10.1039/c39910000573
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A tetrahedral boronic acid-beta-lactamase complex formed by treatment of the P99 beta-lactamase enzyme from Enterobacter cloacae with 3-dansylamidophenylboronic acid has been directly observed using B-11 NMR spectroscopy.
引用
收藏
页码:573 / 574
页数:2
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