CONFOCAL ANALYSIS OF FLUORESCENT BEAD UPTAKE BY MOUSE PEYER PATCH FOLLICLE-ASSOCIATED M-CELLS

被引：63

作者：

PORTA, C

JAMES, PS

PHILLIPS, AD

SAVIDGE, TC

SMITH, MW

CREMASCHI, D

机构：

[1] AFRC,INST ANIM PHYSIOL & GENET RES,CAMBRIDGE CB2 4AT,ENGLAND

[2] UNIV MILAN,DIPARTIMENTO FISIOL & BIOCHIM GEN,I-20133 MILAN,ITALY

[3] QUEEN ELIZABETH HOSP CHILDREN,DEPT EM,LONDON E2 8PS,ENGLAND

来源：

EXPERIMENTAL PHYSIOLOGY | 1992年 / 77卷 / 06期

关键词：

D O I：

10.1113/expphysiol.1992.sp003662

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Latex beads coated with secretory immunoglobulin (IgA) instilled into mouse intestinal loops are taken up by M cells present in Peyer's patch follicle-associated epithelial tissue. Bead adsorption and uptake is greater at the edge compared with the apex of follicle domes. Coating beads with bovine serum albumin (BSA) causes a fourfold reduction in adsorption and a twentyfold reduction in uptake. Results demonstrate selectivity between adsorption and uptake and between the ability of different proteins to facilitate uptake.

引用

页码：929 / 932

页数：4

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