TRISOMY-6 AS THE SOLE CHROMOSOME ABNORMALITY IN MYELOID DISORDERS

被引：19

作者：

JONVEAUX, P

FENAUX, P

BERGER, R

机构：

[1] INST GENET MOLEC,INSERM,U301,F-75010 PARIS,FRANCE

[2] INST GENET MOLEC,CNRS,SDI 19654 I,F-75010 PARIS,FRANCE

[3] HOP ST LOUIS,CENT HEMATOL LAB,PARIS,FRANCE

[4] HOP C HURIEZ,SERV MALAD SANG,LILLE,FRANCE

来源：

CANCER GENETICS AND CYTOGENETICS | 1994年 / 74卷 / 02期

关键词：

D O I：

10.1016/0165-4608(94)90015-9

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Trisomy 6 was the sole chromosomal abnormality detected in two patients with myeloid disorders in relapse. One had a refractory anemia with excess of blasts and the other acute myeloblastic leukemia. Simple trisomy 6 has been reported in patients with myeloid disorders, marrow hypoplasia, acute myeloid leukemia, and ''preleukemia.'' The prognostic significance of this nonrandom chromosomal abnormality is discussed.

引用

页码：150 / 152

页数：3

共 14 条

[1]

APPELBAUM FR, 1987, EXP HEMATOL, V15, P1134

[2]

BENEDICT WF, 1979, BLOOD, V54, P818

[3] TRISOMY 6 ASSOCIATED WITH APLASTIC-ANEMIA [J].