EVIDENCE FOR THE GENERAL BASE MECHANISM IN CARBOXYPEPTIDASE A-CATALYZED REACTIONS - PARTITIONING STUDIES ON NUCLEOPHILES AND H-2 O-18 KINETIC ISOTOPE EFFECTS

被引：34

作者：

BRESLOW, R

CHIN, J

HILVERT, D

TRAINOR, G

机构：

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-PHYSICAL SCIENCES | 1983年 / 80卷 / 14期

关键词：

D O I：

10.1073/pnas.80.14.4585

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：4585 / 4589

页数：5

共 31 条

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[2] COOPERATIVE CATALYSIS OF CLEAVAGE OF AN AMIDE BY CARBOXYLATE AND PHENOLIC GROUPS IN A CARBOXYPEPTIDASE A MODEL
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MCCLURE, DE
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (01) : 258 - 259
[3] VERY FAST ZINC-CATALYZED HYDROLYSIS OF AN ANHYDRIDE - MODEL FOR RATE AND MECHANISM OF CARBOXYPEPTIDASE A CATALYSIS
BRESLOW, R
MCCLURE, DE
BROWN, RS
EISENACH, J
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1975, 97 (01) : 194 - 195
[4] UNIFIED PICTURE OF MECHANISMS OF CATALYSIS BY CARBOXYPEPTIDASE
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WERNICK, DL
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (04) : 1303 - 1307
[5] Breslow R, 1969, ORGANIC REACTION MEC
[6] PH-DEPENDENCE OF HYDROLYSIS OF HIPPURIC ACID-ESTERS BY CARBOXYPEPTIDASE-A
BUNTING, JW
CHU, SST
[J]. BIOCHEMISTRY, 1976, 15 (15) : 3237 - 3244
[7] DIRECT ANALYSIS OF STABLE ISOTOPES WITH A QUADRUPOLE MASS-SPECTROMETER
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FIES, WF
STORY, MS
[J]. ANALYTICAL CHEMISTRY, 1974, 46 (04) : A453 - &
[8] SOME REACTIONS OF PHENOLIC MALEAMIC ACIDS RELEVANT TO CARBOXYPEPTIDASE CATALYSIS
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BRESLOW, R
[J]. TETRAHEDRON LETTERS, 1982, 23 (41) : 4221 - 4224
[9] Cleland W W, 1977, Adv Enzymol Relat Areas Mol Biol, V45, P273
[10] COLEMAN JE, 1961, J BIOL CHEM, V236, P2244

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