ISOXICAM AND RELATED 4-HYDROXY-N-ISOXAZOLYL-2H-1,2-BENZOTHIAZINE-3-CARBOXAMIDE 1,1-DIOXIDES - POTENT NON-STEROIDAL ANTI-INFLAMMATORY AGENTS

被引：52

作者：

ZINNES, H ^{[1
]}

SIRCAR, JC ^{[1
]}

LINDO, N ^{[1
]}

SCHWARTZ, ML ^{[1
]}

FABIAN, AC ^{[1
]}

SHAVEL, J ^{[1
]}

KASULANIS, CF ^{[1
]}

GENZER, JD ^{[1
]}

LUTOMSKI, C ^{[1
]}

DIPASQUALE, G ^{[1
]}

机构：

[1] WARNER LAMBERT PARKE DAVIS,DIV PHARMACEUT RES,ANN ARBOR,MI 48105

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1982年 / 25卷 / 01期

关键词：

D O I：

10.1021/jm00343a003

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：12 / 18

页数：7

共 18 条

[1] EXCRETION AND METABOLISM OF A NONSTEROIDAL ANTIINFLAMMATORY AGENT, 4-HYDROXY-2-METHYL-2H-1,2-BENZOTHIAZINE-3-CARBOXANILIDE 1,1-DIOXIDE, IN RAT, DOG, MONKEY, AND MAN [J].

CHIAINI, J ;

WISEMAN, EH ;

LOMBARDINO, JG .

JOURNAL OF MEDICINAL CHEMISTRY, 1971, 14 (12) :1175-+

[2] METHYLSULFINYL CARBANION (CH3-SO-CH2-) . FORMATION AND APPLICATIONS TO ORGANIC SYNTHESIS [J].

COREY, EJ ;

CHAYKOVSKY, M .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1965, 87 (06) :1345-+

[3] ANTI-INFLAMMATORY PROPERTIES OF ISOXICAM(4-HYDROXY-2-METHYL-N-[5-METHYL-3-ISOXOLYL-2H-1,2-BENZOTHIAZINE-3-CARBOXAMIDE 1,1-DIOXIDE]) [J].

DIPASQUALE, G ;

RASSAERT, C ;

RICHTER, R ;

WELAJ, P ;

GINGOLD, J ;

SINGER, R .

AGENTS AND ACTIONS, 1975, 5 (03) :256-263

[4]

DIPASQUALE G, 1973, ARCH INT PHARMACOD T, V203, P92

[5]

GENZER JD, 1976, Patent No. 3960856

[6]

GINSBERG F, 1980, CURR THER RES CLIN E, V28, P570

[7]

IWAN I, 1966, CHEM PHARM BULL, V14, P1277

[8] SUDOXICAM AND RELATED N-HETEROCYCLIC CARBOXAMIDES OF 4-HYDROXY-2H-1,2-BENZOTHIAZINE 1,1-DIOXIDE - POTENT NONSTEROIDAL ANTIINFLAMMATORY AGENTS [J].

LOMBARDI.JG ;

WISEMAN, EH .

JOURNAL OF MEDICINAL CHEMISTRY, 1972, 15 (08) :848-&

[9] POTENT ANTIINFLAMMATORY N-HETEROCYCLIC 3-CARBOXAMIDES OF 4-HYDROXY-2-METHYL-2H-1,2-BENZOTHIAZINE 1,1-DIOXIDE [J].

LOMBARDI.JG ;

WISEMAN, EH ;

CHIAINI, J .

JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (05) :493-496

[10] SYNTHESIS AND ANTIINFLAMMATORY ACTIVITY OF SOME 3-CARBOXAMIDES OF 2-ALKYL-4-HYDROXY-2H-1,2-BENZOTHIAZINE 1,1-DIOXIDE [J].

LOMBARDINO, JG ;

WISEMAN, EH ;

MCLAMORE, WM .

JOURNAL OF MEDICINAL CHEMISTRY, 1971, 14 (12) :1171-+

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