B-11 IMAGING WITH A 3-DIMENSIONAL RECONSTRUCTION METHOD

被引:99
作者
GLOVER, GH
PAULY, JM
BRADSHAW, KM
机构
[1] Department of Diagnostic Radiology, Stanford School of Medicine, Stanford, California, 94305-5105, S-047
[2] Electrical Engineering Department, Stanford University, Stanford, California
[3] EG & G Idaho Inc., Idaho National Engineering Laboratory, Idaho Falls
[4] Medical Imaging Research Laboratory, Department of Radiology, University of Utah, Salt Lake
来源
JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING | 1992年 / 2卷 / 01期
关键词
BORON; IMAGE PROCESSING; MAGNETIC RESONANCE (MR); SPECTROSCOPY; NEOPLASMS; THERAPY; PHANTOMS; PULSE SEQUENCES; RECONSTRUCTION ALGORITHMS; 3-DIMENSIONAL IMAGING;
D O I
10.1002/jmri.1880020109
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
A three-dimensional projection reconstruction technique is described for imaging boron-11 distributions, with potential application to boron neutron capture therapy. The method samples a spherical volume of k space uniformly to obtain a 32 x 32 x 32 matrix with voxel size of 0.42 cm3. A signal-to-noise ratio (S/N) of 3 was obtained in 8.5 minutes in a phantom containing 75-mu-g/mL of boron in borocaptate sodium (BSH). Images were obtained in a dog after cessation of an intravenous infusion of BSH and again 30 minutes later, with a maximum boron S/N of about 12. Boron levels in the brain dropped about 6%-8% and were more diffusely distributed on the images obtained 30 minutes after BSH infusion.
引用
收藏
页码:47 / 52
页数:6
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